2024-03-28T17:10:27Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/43982022-04-29T12:02:47Zcom_10259_4862com_10259_5086com_10259_2604col_10259_4863
Fernández Natal, Isabel
e36a25a1-d470-4ce6-bbf1-d2b47990abd3
500
Rodríguez Lázaro, David
478
500
Marrodán Ciordia, T.
476c8b98-006b-4bc4-a562-9c579b56feba
500
Sáez Nieto, J. A.
d614fb16-fd73-4429-b084-6f523f09aa56
500
Valdezate Ramos, S.
3ad3693c-50c0-42ff-bef0-e5e9f33194a2
500
Rodríguez Pollán, R. H.
ab5dc450-834d-4c35-b7ce-82d9f016b36e
500
Tauch, A.
141c4ffc-93fc-4e35-9b2b-ea8ee6ca16c2
500
Soriano, F.
4a376180-9f85-4972-9f72-657c99f3f90c
500
2017-03-30T11:34:29Z
2017-03-30T11:34:29Z
2016-11
http://hdl.handle.net/10259/4398
Human infections associated with Corynebacterium kroppenstedtii are rarely reported, and this organism is usually described as antibiotic sensitive. Almost all published cases of C. kroppenstedtii infections have been associated with breast pathology in women and have been described in New Zealand, France, Canada, India and Japan. Here we describe the microbiologic characteristics of two strains isolated from two women diagnosed of granulomatous mastitis in Spain. One C. kroppenstedtii isolate was antibiotic sensitive while the other was multidrug resistant. Biochemical identification was possible using a wide battery of methods including API Coryne V2.0, API Strep, API NH, API NE, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and 16S rRNA gene amplification and sequencing. Antimicrobial susceptibility to 28 antibiotics as determined by Etest showed one isolate being sensitive to benzylpenicillin, ciprofloxacin, moxifloxacin, gentamicin, vancomycin, clindamycin, tetracycline, linezolid and rifampin. The second isolate showed resistance to ciprofloxacin, moxifloxacin, clindamycin, tetracycline and rifampin. The multidrug-resistant isolate contained the erm(X), tet(W), cmx, aphA1-IAB, strAB and sul1 resistance genes known from the R plasmid pJA144188 of Corynebacterium resistens. These genes were absent in the genome of the antibiotic-sensitive isolate. This report confirms the tropism of this microorganism for women's breasts and presents the first description of a multidrug-resistant C. kroppenstedtii strain.
Gerencia Regional de Salud, Junta de Castilla y León, Spain, research project GRS 698/A/2011
application/pdf
eng
Elsevier
New Microbes and New Infections. 2016, V. 14, p. 93–97
http://dx.doi.org/10.1016/j.nmni.2016.09.006
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
Antimicrobial susceptibility
Corynebacterium kroppenstedtii
granulomatous mastitis
MALDI-TOF MS
multidrug-resistant isolate
Microbiology
Microbiología
Characterization and antimicrobial susceptibility of one antibiotic-sensitive and one multidrug-resistant Corynebacterium kroppenstedtii strain isolated from patients with granulomatous mastitis
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
CC-LICENSE
license_rdf
license_rdf
application/rdf+xml; charset=utf-8
805
https://riubu.ubu.es/bitstream/10259/4398/8/license_rdf
4460e5956bc1d1639be9ae6146a50347
MD5
8
THUMBNAIL
Fernández-NMNI_2016.pdf.jpg
Fernández-NMNI_2016.pdf.jpg
IM Thumbnail
image/jpeg
4789
https://riubu.ubu.es/bitstream/10259/4398/7/Fern%c3%a1ndez-NMNI_2016.pdf.jpg
286751ba4fb72a0d00b39bf4273e0661
MD5
7
ORIGINAL
Fernández-NMNI_2016.pdf
Fernández-NMNI_2016.pdf
application/pdf
68314
https://riubu.ubu.es/bitstream/10259/4398/1/Fern%c3%a1ndez-NMNI_2016.pdf
9540deb088e4a7385c426226738a7014
MD5
1
LICENSE
license.txt
license.txt
text/plain; charset=utf-8
999
https://riubu.ubu.es/bitstream/10259/4398/5/license.txt
b295bcbce42e2caabeb0c623d3860c06
MD5
5
TEXT
Fernández-NMNI_2016.pdf.txt
Fernández-NMNI_2016.pdf.txt
Extracted text
text/plain
23674
https://riubu.ubu.es/bitstream/10259/4398/6/Fern%c3%a1ndez-NMNI_2016.pdf.txt
e682430fd4400bbd069fd9906b3b5a16
MD5
6
10259/4398
oai:riubu.ubu.es:10259/4398
2022-04-29 14:02:47.852
Repositorio Institucional de la Universidad de Burgos
bubrep@ubu.es
RWwgYXV0b3IgY29tbyDDum5pY28gdGl0dWxhciBkZSBsb3MgZGVyZWNob3MgZGUgcHJvcGllZGFkIGludGVsZWN0dWFsIGRlIGxhIG9icmEsIG8gZGlzcG9uaWVuZG8gZGUgbG9zIGRlYmlkb3MgcGVybWlzb3MgZGUgbG9zIG90cm9zIHRpdHVsYXJlcywgc2kgbG9zIGh1YmllcmEsIHkgZW4gdmlydHVkIGRlIGxvcyBkZXJlY2hvcyBxdWUgbGUgY29uZmllcmUgbGEgbGVnaXNsYWNpw7NuIHZpZ2VudGUgc29icmUgcHJvcGllZGFkIGludGVsZWN0dWFsIHkgZGVyZWNob3MgZGUgYXV0b3IsIA0KQVVUT1JJWkEgYSBsYSBVbml2ZXJzaWRhZCBkZSBCdXJnb3MgYSBkaWZ1bmRpciwgZGUgbWFuZXJhIGdyYXR1aXRhLCBlbCBjb250ZW5pZG8gZGUgbG9zIGFyY2hpdm9zIGRpZ2l0YWxlcyBxdWUgY29ycmVzcG9uZGVuIGFsIGRvY3VtZW50byBkZXNjcml0byBhbnRlcmlvcm1lbnRlLCBjb24gY2Fyw6FjdGVyIG5vIGV4Y2x1c2l2byB5IGRlIG1hbmVyYSBww7pibGljYSBlbiBhY2Nlc28gYWJpZXJ0byBhIHRyYXbDqXMgZGUgSW50ZXJuZXQsIHBhcmEgbG8gcXVlIGxhIEJpYmxpb3RlY2EgcHJvY2VkZXLDoSBhIGFyY2hpdmFybG9zIGVuIGVsIFJlcG9zaXRvcmlvIEluc3RpdHVjaW9uYWwuIEFzaW1pc21vIGF1dG9yaXphIGEgbGEgVW5pdmVyc2lkYWQgZGUgQnVyZ29zIGEgcmVhbGl6YXIgbGFzIHRyYW5zZm9ybWFjaW9uZXMgbmVjZXNhcmlhcyBkZSBmb3JtYXRvLCBubyBkZSBjb250ZW5pZG8sIHBhcmEgZ2FyYW50aXphciBsYSBwcmVzZXJ2YWNpw7NuIHkgZWwgYWNjZXNvIGVuIGVsIGZ1dHVyby4NCg0KRWwgYXV0b3IgZGlzcG9uZSwgZW4gdG9kbyBjYXNvLCBkZWwgZGVyZWNobyBhIHJldm9jYXIgZXN0YSBhdXRvcml6YWNpw7NuLg0KDQpMYSBjZXNpw7NuIGRlIGRlcmVjaG9zIGRlIGVzdGEgb2JyYSBzZSBlbmN1ZW50cmEgc3VqZXRhIGEgbGEgbGVnaXNsYWNpw7NuIHZpZ2VudGUgc29icmUgcHJvcGllZGFkIGludGVsZWN0dWFsIHkgZGVyZWNob3MgZGUgYXV0b3Iu