2024-03-29T13:58:29Zhttps://riubu.ubu.es/oai/requestoai:riubu.ubu.es:10259/61192022-11-15T13:51:45Zcom_10259_3844com_10259_5086com_10259_2604col_10259_3845
Vulcano, Fabio
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Kovtun, Alessandro
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Bettini, Cristian
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600
Xia, Zhenyuan
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600
Liscio, Andrea
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600
Terzi, Fabio
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600
Heras Vidaurre, Aránzazu
273
600
Colina Santamaría, Álvaro
122
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Zanfrognini, Barbara
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Melucci, Manuela
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2021-11-08T12:02:02Z
2021-11-08T12:02:02Z
2020-04
2053-1583
http://hdl.handle.net/10259/6119
10.1088/2053-1583/ab734f
2053-1583
We describe a nanocomposite material for the electrochemical detection of β-nicotinamide adenine dinucleotide (NADH), a coenzyme involved in redox reactions of all living cells and in the detection of many organic species by electrochemical biosensors. The composite is made of nanosheets of electrochemically exfoliated graphene oxide (EGO) covalently functionalized with dopamine (DP) molecules. The EGODP material finally obtained is rich of 1,2-dihydroxyphenyl moieties and is able to detect NADH at a particular low potential value with higher sensitivity with respect to pristine EGO.
To study the effectiveness of 1,2-dihydroxyphenyl moieties in inducing electrocatalytic oxidation of NADH, we combined standard voltammetric techniques with UV–Vis absorption spectroelectrochemistry, which allowed us to measure the variations in composition occurring at the electrode|solution interface, i.e. to measure the consumption rate of NADH.
Spectroelectrochemical tests performed by polarising the electrode at a fixed potential value were finally used to compare the performance of EGODP with both EGO and EGO-DP blend (MIX) for the detection of NADH. The covalently functionalized EGO (EGODP) shows sensitivity to NADH up to 300 M−1, around 180 % and 140 % better than either pristine EGO or MIX, respectively.
Spanish Ministerio de Economía y Competitividad (Grants CTQ2017-83935-R-AEI/FEDERUE), Ministerio de Ciencia, Innovación y Universidades (RED2018-102412-T) and Junta de Castilla y León (Grant BU297P18).
application/pdf
spa
IOP Publishing
2D Materials. 2020, V. 7, n. 2, 024007
https://doi.org/10.1088/2053-1583/ab734f
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/CTQ2017-83935-R/ES/ESPECTROELECTROQUIMICA RAMAN CUANTITATIVA
info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/ RED2018-102412-T/ES/RED DE SENSORES Y BIOSENSORES ELECTROQUIMICOS
info:eu-repo/grantAgreement/Junta de Castilla y León//BU297P18//Fusión de técnicas espectroelectroquímicas avanzadas
Attribution-NonCommercial-NoDerivs 3.0 Unported
http://creativecommons.org/licenses/by-nc-nd/3.0/
info:eu-repo/semantics/openAccess
graphene oxide
spectroelectrochemistry
chemical functionalization
1,2-dihydroxyphenyl moieties
NADH
Química analítica
Chemistry, Analytic
Dopamine-functionalized graphene oxide as a high-performance material for biosensing
info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
THUMBNAIL
Vulcano-2Dmaterials_2020.pdf.jpg
Vulcano-2Dmaterials_2020.pdf.jpg
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LICENSE
license.txt
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https://riubu.ubu.es/bitstream/10259/6119/3/license.txt
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ORIGINAL
Vulcano-2Dmaterials_2020.pdf
Vulcano-2Dmaterials_2020.pdf
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https://riubu.ubu.es/bitstream/10259/6119/1/Vulcano-2Dmaterials_2020.pdf
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10259/6119
oai:riubu.ubu.es:10259/6119
2022-11-15 14:51:45.639
Repositorio Institucional de la Universidad de Burgos
bubrep@ubu.es
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