RT info:eu-repo/semantics/article T1 Epigenetic profiling linked to multisystem inflammatory syndrome in children (MIS-C): A multicenter, retrospective study A1 Davalos, Veronica A1 García-Prieto, Carlos A. A1 Ferrer, Gerardo A1 Aguilera-Albesa, Sergio A1 Valencia Ramos, Juan A1 Rodríguez-Palmero, Agustí A1 Ruiz, Montserrat A1 Planas-Serra, Laura A1 Jordan, Iolanda A1 Alegría, Iosune A1 Flores-Pérez, Patricia A1 Cantarín, Verónica A1 Fumadó, Victoria A1 Viadero, Maria Teresa A1 Rodrigo, Carlos A1 Méndez-Hernández, Maria A1 López-Granados, Eduardo A1 Colobran, Roger A1 Rivière, Jacques G. A1 Soler-Palacín, Pere A1 Pujol, Aurora A1 Esteller, Manel K1 Multisystem inflammatory syndrome in children K1 COVID-19 K1 Kawasaki disease K1 Epigenetics K1 DNA methylation K1 Medicina K1 Medicine AB Most children and adolescents infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain asymptomatic or develop a mild coronavirus disease 2019 (COVID-19) that usually does not require medical intervention. However, a small proportion of pediatric patients develop a severe clinical condition, multisystem inflammatory syndrome in children (MIS-C). The involvement of epigenetics in the control of the immune response and viral activity prompted us to carry out an epigenomic study to uncover target loci regulated by DNA methylation that could be altered upon the appearance of MIS-C. PB Elsevier SN 2589-5370 YR 2022 FD 2022-08 LK http://hdl.handle.net/10259/10037 UL http://hdl.handle.net/10259/10037 LA eng NO Unstoppable campaign of Josep Carreras Leukaemia Foundation, Fundacio La Marat o de TV3, Cellex Foundation and CERCA Programme/Generalitat de Catalunya. DS Repositorio Institucional de la Universidad de Burgos RD 03-mar-2025