RT info:eu-repo/semantics/article T1 Impact of different nebulisation systems on patient comfort in bronchiolitis: a randomised controlled cross-over trial A1 Valencia Ramos, Juan A1 Ochoa Sangrador, Carlos A1 García, María A1 Oyagüez, Pablo A1 Arnaez, Juan K1 Bronchiolitis K1 Comfort K1 COMFORT-Behavior scale K1 Family-centered care K1 Pediatric Critical Care K1 Bronquiolitis K1 Enfermedades infecciosas en niños K1 Communicable diseases in children AB Objective: To test the hypothesis that greater comfort is achieved using a nebuliser integrated into a high-flow nasal cannula (nebulisation system integrated in high-flow nasal cannula (NHF)) than using a jet nebuliser (JN), and to explore differences in analgesia requirement and the possibility of feeding during nebulisation.Design: Randomised cross-over trial.Setting: Paediatric intensive care unit.Patients: Children aged <24 months diagnosed with bronchiolitis between November 2016 and May 2017.Interventions: Nebulisations using NHF and JN.Main outcome measures: COMFORT–Behaviour Scale (CBS) and Numerical Rating Comfort Scale (NRSc) were used to measure comfort, and Numerical Rating Satisfaction Scale (NRSs) was used to assess satisfaction before, during and after nebulisation. Other variables included feeding, analgesia, need for being held and respiratory and heart rates.Results: Thirty-three children with 233 nebulisations were included in the study. The median age was 3.0 (IQR 2–9) months. Comfort and satisfaction were greater with NHF than with JN. The median staff-recorded CBS, NRSc and NRSs scores for NHF versus JN were 13 (IQR 9–15) vs 17 (IQR 13–23), 8 (IQR 7–0) vs 7 (IQR 4–8), and 4 (IQR 3–4) vs 2 (IQR 2–3), respectively; and caregiver-recorded scores were 12 (IQR 10–15) vs 19 (IQR 13–24), 9 (IQR 7–10) vs 4 (IQR 1–6), and 4 (IQR 3–4) vs 2 (IQR 1–3), respectively (p<0.001). Children who received NHF had lower cardiac and respiratory rates, needed to be held less often during therapy and required less analgesia (p<0.001).Conclusion: Nebulisation through NHF appears to be a better alternative to JN in terms of comfort and satisfaction as well as making feeding possible during nebulisation. PB BMJ Publishing Group SN 0003-9888 YR 2022 FD 2022-12 LK http://hdl.handle.net/10259/10046 UL http://hdl.handle.net/10259/10046 LA eng NO This study was supported by Fundación Ernesto Sánchez Villares (FESV) (01/2017), and Aerogen (Philips) provided nebulisers free of charge. The opinions, results and conclusions reported in this paper are those of the authors and are independent of funding sources. No endorsement by FESV is intended or inferred. DS Repositorio Institucional de la Universidad de Burgos RD 03-mar-2025