RT info:eu-repo/semantics/article T1 Observational study of newborn infant parasympathetic evaluation as a comfort system in awake patients admitted to a pediatric intensive care unit A1 Valencia Ramos, Juan A1 Arnaez, Juan A1 Calvo Meruelo, Sara A1 Gomez, Fernando A1 Blanco Gómez, Isabel del K1 Comfort K1 Newborn infant parasympathetic evaluation K1 COMFORT Behavior Scale K1 Nebulization K1 Bronchiolitis K1 Bronquiolitis K1 Enfermedades infecciosas en niños K1 Communicable diseases in children AB To compare the newborn infant parasympathetic evaluation system (NIPE) scores with a validated clinical scale using two different nebulizers in children with bronchiolitis admitted to a PICU. Comfort was evaluated using the COMFORT-behavior scale (CBS) before (T1), during (T2) and after (T3) each nebulization. In order to compare NIPE and CBS values during the whole T1 to T3 period, the variable Dif-CBS was defined as the difference between maximal and minimal CBS scores, and Dif-NIPE as the difference between 75th and 25th percentile NIPE values. Analyses were carried out, firstly for the total of nebulizations and secondly comparing two different nebulization systems: a jet nebulizer (JN) and a nebulizer integrated in high flow nasal cannulas (NHF). 84 nebulizations were recorded on 14 patients with a median [25th–75th percentile] age of 6 months (3.1–9.5). A Dif-CBS of 4 points (2–7), as well as changes in CBS scores between T1 and T2, defined the nebulization as a discomfort stimulus. The NIPE system, represented as the Dif-NIPE, showed a median variation of 9 points (7–10), and was poorly correlated to Dif-CBS [rs 0.162 (P = 0.142)]. Discomfort during nebulization, assessed by CBS was greater with the JN system compared to NHF: 17 (13–22) vs 13 (9–15) (P = 0.001). NIPE monitoring detected no significant differences between both nebulization systems (P = 0.706). NIPE monitoring showed a variation in comfort during nebulization in the patient with bronchiolitis, though correlation with CBS was poor. Further research is required before NIPE can be suggested as a comfort monitoring system for the awake infant. PB Springer SN 1387-1307 YR 2019 FD 2019-02 LK http://hdl.handle.net/10259/10048 UL http://hdl.handle.net/10259/10048 LA eng DS Repositorio Institucional de la Universidad de Burgos RD 03-mar-2025