RT info:eu-repo/semantics/article
T1 Predictors for Anastomotic Leak, Postoperative Complications, and Mortality After Right Colectomy for Cancer: Results From an International Snapshot Audit
A1 Frasson, Matteo
A1 Battersby, Nick J.
A1 Reoyo Pascual, José Felipe
A1 2015 European Society of Coloproctology Collaborating Group
K1 Anastomotic leak
K1 Colon cancer
K1 Postoperative outcome
K1 Right colectomy
K1 Aparato digestivo-Enfermedades
K1 Digestive organs-Diseases
K1 Salud
K1 Health
K1 Medicina
K1 Medicine
AB BACKGROUND: A right hemicolectomy is among the most commonly performed operations for colon cancer, but modern high-quality, multination data addressing the morbidity and mortality rates are lacking.OBJECTIVE: This study reports the morbidity and mortality rates for right-sided colon cancer and identifies predictors for unfavorable short-term outcome after right hemicolectomy.DESIGN: This was a snapshot observational prospective study.SETTING: The study was conducted as a multicenter international study.PATIENTS: The 2015 European Society of Coloproctology snapshot study was a prospective multicenter international series that included all patients undergoing elective or emergency right hemicolectomy or ileocecal resection over a 2-month period in early 2015. This is a subanalysis of the colon cancer cohort of patients.MAIN OUTCOME MEASURES: Predictors for anastomotic leak and 30-day postoperative morbidity and mortality were assessed using multivariable mixed-effect logistic regression models after variables selection with the Lasso method.RESULTS: Of the 2515 included patients, an anastomosis was performed in 97.2% (n = 2444), handsewn in 38.5% (n = 940) and stapled in 61.5% (n = 1504) cases. The overall anastomotic leak rate was 7.4% (180/2444), 30-day morbidity was 38.0% (n = 956), and mortality was 2.6% (n = 66). Patients with anastomotic leak had a significantly increased mortality rate (10.6% vs 1.6% no-leak patients; p > 0.001). At multivariable analysis the following variables were associated with anastomotic leak: longer duration of surgery (OR = 1.007 per min; p = 0.0037), open approach (OR = 1.9; p = 0.0037), and stapled anastomosis (OR = 1.5; p = 0.041).LIMITATIONS: This is an observational study, and therefore selection bias could be present. For this reason, a multivariable logistic regression model was performed, trying to correct possible confounding factors.CONCLUSIONS: Anastomotic leak after oncologic right hemicolectomy is a frequent complication, and it is associated with increased mortality. The key contributing surgical factors for anastomotic leak were anastomotic technique, surgical approach, and duration of surgery. See Video Abstract at https://links.lww.com/DCR/B165.
PB Wolters Kluwer
SN 0012-3706
YR 2020
FD 2020-05
LK http://hdl.handle.net/10259/10134
UL http://hdl.handle.net/10259/10134
LA spa
DS Repositorio Institucional de la Universidad de Burgos
RD 22-feb-2025