RT info:eu-repo/semantics/article
T1 Self-assembling Depsipeptides on Aggregation-Induced Emission Luminogens: A New Way to Create Programmable Nanovesicles and Soft Nanocarriers
A1 Hernando Muñoz, Carla
A1 Revilla Cuesta, Andrea
A1 Abajo Cuadrado, Irene
A1 Andreini, Camilla
A1 Torroba Pérez, Tomás
A1 Busto Vázquez, Natalia
A1 Fernández Zoppino, Darío
A1 Perdomo Hernández, Germán M.
A1 Acosta, Gerardo
A1 Royo, Miriam
A1 Gutiérrez Reguera, Javier
A1 Spinello, Angelo
A1 Barone, Giampaolo
A1 Black, Dominic
A1 Pal, Robert
K1 Fluorescent materials
K1 Aggregation induced emission materials
K1 Active transport
K1 Nanoencapsulation
K1 Programmed cytotoxity
K1 Química orgánica
K1 Chemistry, Organic
K1 Nanotecnología
K1 Nanotechnology
K1 Química física
K1 Chemistry, Physical and theoretical
AB We introduce the proof of concept of a newmethodology to produce robust hollow nanovesicles stable inwater or mixtures of water and organic solvents. The bottom-upproduced nanovesicles are formed by the self-assembly ofdepsipeptide chains of natural origin combined with newaggregation-induced emission luminogens that function as constitu-tional vesicle-forming moieties and fluorescent indicators of thestructure of the nanovesicle. The newly formed nanovesicles arerobust enough to be used to carry large molecules such asphysiological peptides without losing their structural characteristics,acting as programmable nanocarrier systems within living cells asTrojan horse systems, constituting a new approach to activetransport and nanoencapsulation.
PB American Chemical Society
SN 1944-8244
YR 2025
FD 2025-01
LK http://hdl.handle.net/10259/10163
UL http://hdl.handle.net/10259/10163
LA eng
NO This research was funded by the Ministerio de Ciencia,Innovación y Universidades of Spain (Grants PDC2022−133955-I00 and PID2022−142318NB-I00). C.H.-M. thanksthe Secretaría General de Universidades of Spain for an FPU21/01473 Grant.
DS Repositorio Institucional de la Universidad de Burgos
RD 23-feb-2025