RT info:eu-repo/semantics/article
T1 Determination of ofloxacin in urine using UV/Vis absorption spectroelectrochemistry
A1 Olmo Alonso, Fabiola
A1 Colina Santamaría, Álvaro
A1 Heras Vidaurre, Aránzazu
K1 Ofloxacin
K1 Urine
K1 Spectroelectrochemistry
K1 Multivariate analysis
K1 Química analítica
K1 Chemistry, Analytic
K1 Electroquímica
K1 Electrochemistry
AB UV–Vis absorption spectroelectrochemistry has been selected as a suitable multiresponse technique to determinethe fluoroquinolone ofloxacin in urine samples without any previous pretreatment. Due to the modification of theworking electrode surface during the oxidation of this antibiotic, the electrode has to be replaced or polishedbetween measurements. A new spectroelectrochemistry cell has been developed, which allows in an simple wayto perform reproducible experiments with different screen-printed electrodes. The new cell has been used toperform analysis in a complex matrix such as urine. Due to the trilinear character of the spectroelectrochemicaldata, PARAFAC has been used to determine ofloxacin with very good figures of merit, demonstrating thecapability of trilinear methods to avoid the influence of some interfering compounds.
PB Elsevier
SN 0026-265X
YR 2024
FD 2024-03
LK http://hdl.handle.net/10259/10195
UL http://hdl.handle.net/10259/10195
LA eng
NO Ministerio de Ciencia e Innovacion ´ and Agencia Estatal de Inves tigacion ´ (Grant numbers: MCIN/AEI/10.13039/501100011033, PID2020-113154RB-C21), Ministerio de Ciencia, Innovacion ´ y Uni versidades (Grant number: RED2022-134120-T), Junta de Castilla y Leon ´ and European Regional Development Fund (Grant number: BU036P23) are gratefully acknowledged for funding this work.
DS Repositorio Institucional de la Universidad de Burgos
RD 22-feb-2025