RT dataset
T1 Dataset of the work “UV Vis absorption spectroelectrochemistry of folic acid”
A1 Olmo Alonso, Fabiola
A1 Rodríguez Rubio, Andrea
A1 Colina Santamaría, Álvaro
A1 Heras Vidaurre, Aránzazu
K1 Vitamin B9
K1 Pharmaceutical drug
K1 Electrochemistry
K1 UV/Vis absorption spectroscopy
K1 Química analítica
K1 Chemistry, Analytic
AB UV/Vis absorption spectroelectrochemistry is a very promising analytical technique due to the complementary information that is simultaneously obtained from electrochemistry and spectroscopy. In this work, this technique is used in a parallel configuration to study the oxidation of folic acid in alkaline medium. Herein, UV/Vis absorption spectroelectrochemistry has been used to detect both the oxidation products and the folic acid consumed at the electrode/solution interface, allowing us to develop an analytical protocol to quantify vitamin B9 in pharmaceutical tablets. Linear ranges of three orders of magnitude have been achieved in basic medium (pH = 12.9), obtaining high repeatability and low detection limits. The spectroelectrochemical determination of folic acid in pharmaceutical tablets at alkaline pH values is particularly interesting because of the changes that occur in the optical signal during the electrochemical oxidation of FA, providing results with very good figures of merit and demonstrating the utility and versatility of this hyphenated technique, UV/Vis absorption spectroelectrochemistry.
PB Universidad de Burgos
YR 2024
FD 2024-05-03
LK http://hdl.handle.net/10259/10229
UL http://hdl.handle.net/10259/10229
LA eng
NO Open Access funding provided thanks to the CRUE-CSIC agreement with Springer Nature. Authors acknowledge the financial support from Ministerio de Economía y Competitividad (Grant CTQ2017-83935-R-AEI/FEDERUE), Junta de Castilla y León (Grant BU297P18), and Ministerio de Ciencia, Innovación y Universidades (Grant RED2018-102412-T). F.O. is grateful for the contract funded by Junta de Castilla y León, the European Social Fund, and the Youth Employment Initiative.
DS Repositorio Institucional de la Universidad de Burgos
RD 22-feb-2025