RT info:eu-repo/semantics/article
T1 Molybdenum‐Catalyzed Direct Synthesis of Pyrroles from Nitroarenes with Glycols as Reductants
A1 Gómez Gil, Sara
A1 Suárez Pantiga, Samuel
A1 Pedrosa Sáez, María de los Remedios
A1 Sanz Díez, Roberto
K1 Nitroarenes
K1 Pyrroles
K1 Reduction
K1 Molybdenum
K1 Glycols
K1 Química
K1 Chemistry
K1 Química orgánica
K1 Chemistry, Organic
AB A molybdenum-catalyzed synthesis of N-(hetero)aryl pyrroles directly from inexpensive and commonly available (hetero)nitroarenes via reduction with pinacol and annulation with 1,4-dicarbonyls or cyclobutane-1,2-diols has been described. The process does not require an inert atmosphere and tolerates the presence of air and water. This non-noble catalytic system shows high chemoselectivity, allowing a diverse range of potentially reducible functional groups such as alkynes, alkenes, halogens, cyano, and carbonyls. Moreover, this strategy enables the reuse of a waste byproduct as reactant, facilitating the formation of challenging 1,4-dicarbonyls from accessible cyclobutane-1,2-diols used as reducing agents.
PB Wiley
SN 1615-4150
YR 2024
FD 2024-10
LK http://hdl.handle.net/10259/10505
UL http://hdl.handle.net/10259/10505
LA eng
NO We acknowledge the financial support from Ministerio de Ciencia, Innovación y Universidades (PID2020-115789GB-C21/AEI/10.1039/501100011033 and PDC2021-115789GB-C21), and Junta de Castilla y León and FEDER (BU028P23). S.G.-G. thanks Ministerio de Ciencia, Innovación y Universidades for a FPU predoctoral contract. S.S.-P. thanks Ministerio de Ciencia, Innovación y Universidades and “NextGenerationEU”/PRTR EU for a Ramón y Cajal contract (RYC2021-031533-I).
DS Repositorio Institucional de la Universidad de Burgos
RD 31-may-2025