RT dataset
T1 Dataset of the work “Determination of nicotine in e-liquids by electrochemical generation of surface-enhanced Raman scattering substrates”
A1 Romay García, Luis
A1 Pérez Estébanez, Martín
A1 Heras Vidaurre, Aránzazu
A1 Colina Santamaría, Álvaro
K1 SERS
K1 Spectroelectrochemistry
K1 PARAFAC
K1 Nicotine
K1 E-liquid
K1 Química analítica
K1 Chemistry, Analytic
K1 Electroquímica
K1 Electrochemistry
AB Quantitative methods using surface-enhanced Raman scattering (SERS) for analysis in complex matrices are very attractive due to the high sensitivity and selectivity of this technique. In this work, a novel time-resolved electrochemical surface-enhanced Raman scattering (TR-EC-SERS) analytical method has been developed for the determination of nicotine in e-liquids of electronic cigarettes. One of the main challenges of SERS is its inherent lack of reproducibility. Here, this limitation was mitigated by employing an electrochemical pre-treatment step to generate a homogeneous distribution of silver nanoparticles (Ag-NPs) on a silver screen-printed electrode. The enhanced Raman scattering induced by the Ag-NPs enabled the detection of nicotine at nanomolar levels. The high sensitivity of the method allowed the quantitative analysis of diluted e-liquid samples, mitigating potential interferences from other components present in these complex matrices. Moreover, TR-EC-SERS, coupled with parallel factor analysis (PARAFAC), demonstrated the capability of trilinear spectroelectrochemistry data not only to detect nicotine but also to identify potential interfering compounds without prior knowledge of their spectral signatures. This multivariate approach offers significant potential for the detection of outliers in complex samples.
PB Universidad de Burgos
YR 2025
FD 2025-05-20
LK https://hdl.handle.net/10259/10768
UL https://hdl.handle.net/10259/10768
LA eng
NO ROMAY, Luis, Perez-Estebanez, M., Heras, A., & Colina, A. (2025). Dataset of the work “Determination of nicotine in e-liquids by electrochemical generation of surface-enhanced Raman scattering substrates” [Data set]. Universidad de Burgos. https://doi.org/10.71486/QF7N-2B15
NO Open Access funding provided thanks to the CRUE-CSIC agreement withElsevier B.V. Ministerio de Ciencia e Innovacion and Agencia Estatal de Investigacion (MCIN/AEI/10.13039/501100011033, PID2020-113154RB- C21, PID2023-149188OB-I00) and FEDER, UE, Junta de Castilla y Leon and European Regional Development Fund (Grant number: BU036P23), Ministerio de Ciencia, Innovacion y Universidades (RED2022-134120-T) are gratefully acknowledged for funding this work. L.R. acknowledges Ministerio de Ciencia e Innovacion and Agencia Estatal de Investigacion (MCIN/AEI/ 10.13039/ 501100011033, PIS2020-113154 GB-C21) for the predoctoral contract.
DS Repositorio Institucional de la Universidad de Burgos
RD 09-may-2026