RT info:eu-repo/semantics/article T1 Self-Reported Post-COVID Symptoms at 18 Months After Infection Among Adults in Southern Brazil: A Cross-Sectional Study A1 Brito, Franciele Aline Machado de A1 Laranjeira, Carlos A1 Moroskoski, Márcia A1 Salci, Maria Aparecida A1 Rossoni, Stéfane Lele A1 Baccon, Wanessa Cristina A1 Oliveira, Rosana Rosseto de A1 Marques, Priscila Garcia A1 Góes, Herbert Leopoldo de Freitas A1 Mello, Fernanda Fontes A1 Blaszczak, Flávia Renata Baldissera da Cruz A1 Vissoci, João Ricardo Nickenig A1 Puente Alcaraz, Jesús A1 Facchini, Luiz Augusto A1 Carreira, Lígia K1 SARS-CoV-2 K1 Long Covid K1 Signs and symptoms K1 Cross-sectional K1 Brazil K1 Covid-19 K1 COVID-19 (Disease) K1 Salud pública K1 Public health AB Background/Objectives: Currently, there is a limited understanding of the long-term consequences following acute COVID-19, referred to as long COVID. This cross-sectional study aims to analyze the prevalence of persistent signs and symptoms of long COVID, 18 months after primary SARS-CoV-2 infection in adults in southern Brazil. Methods: Using two national databases (the digital registry of SARS-CoV-2 positive cases), 370 individuals living in the state of Paraná (Brazil) were recruited. Data were collected through telephone interviews conducted in 2021 and 2022. Results: The overall prevalence of long COVID was 66.2% among study participants. During the acute phase of infection, the most common symptom clusters included neurological symptoms (87.0%; n = 318), followed by respiratory (82.0%; n = 301), musculoskeletal (66.0%; n = 241), digestive (50.0%; n = 184), psychological (38.0%; n = 138), and endocrine symptoms (28.0%; n = 104). In the 18 month follow-up, the main persistent symptoms were memory loss (42.7%), fatigue (32.2%), anxiety (23.5%), dyspnea (19.7%), and hair loss (19.7%). The proportion of participants with long COVID was statistically higher in females (73.9%), those with a family income below two minimum wages (94.7%), those who do not practice physical activity (83.3%), those who report poor sleep quality (93.3%), those who use long-term medication (85.9%), those who needed health care in the previous six months (87.3%), those who required professional and/or family care (79.3%), those who were in the ICU (79.0%), and those who used ventilatory support (77.5%). Conclusions: Long COVID is a complex condition that requires long-term monitoring and investment in health services due to its high prevalence and the health consequences in the population. PB MDPI YR 2025 FD 2025-01 LK https://hdl.handle.net/10259/11364 UL https://hdl.handle.net/10259/11364 LA eng NO This work was funded by Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)—grant number: 001/2023. It was also supported by FCT—Fundação para a Ciência e a Tecnologia, I.P. (UIDB/05704/2020 and UIDP/05704/2020) and by the Scientific Employment Stimulus—Institutional Call—[https://doi.org/10.54499/CEECINST/00051/2018/CP1566/CT0012]. DS Repositorio Institucional de la Universidad de Burgos RD 27-abr-2026