RT info:eu-repo/semantics/article
T1 Is Probiotics Supplementation an Appropriate Strategy to Modulate Inflammation in Physically Active Healthy Adults or Athletes? A Systematic Review
A1 Fernández Lázaro, Diego
A1 Sánchez Serrano, Nerea
A1 Rabail, Roshina
A1 Aadil, Rana Muhammad
A1 Mielgo Ayuso, Juan
A1 Radesca Fabiano, Krizia
A1 Garrosa, Evelina
K1 Sport supplementation
K1 Probiotics
K1 Physical activity
K1 Athletes
K1 Cytokines
K1 Inflammation-related biomarkers
K1 Probióticos
K1 Probiotics
AB Supplementation with probiotics in sports is on the rise with the aim of improving health and athletic performance. Since intense exercise-induced muscle damage leads to an inflammatory process by increasing circulating inflammatory cytokines, probiotic supplementation may modulate and correct the inflammation. We systematically reviewed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines in the Scopus, Web of Science, and Medline databases for the 10 years until January 2023. This review aimed to evaluate probiotic supplementation as a strategy for modulating inflammation in healthy physically active adults or athletes. Studies were indexed to assess the effect of probiotic supplementation on cytokine behavior in the inflammatory response in physically active individuals. Of the 136 studies identified in the search, 13 met the inclusion criteria, and their quality was assessed using the McMaster Critical Review Form. The results of these trials indicated a significant improvement in inflammatory cytokines in probiotic-supplemented participants, with a significant increase in anti-inflammatory cytokines (IL-10) and a significant decrease in proinflammatory cytokines (IL-6, TNF-α, and IL-8). This would create uncertainty about probiotics’ effect on interleukins’ behavior after exercise, and further clinical trials are needed to establish a solid basis.
PB MDPI
YR 2023
FD 2023-03
LK https://hdl.handle.net/10259/12109
UL https://hdl.handle.net/10259/12109
LA eng
DS Repositorio Institucional de la Universidad de Burgos
RD 18-sep-2026