RT info:eu-repo/semantics/article
T1 A Practical, One-Pot Synthesis of Highly Substituted Thiophenes and Benzo[b]thiophenes from Bromoenynes and o-Alkynylbromobenzenes
A1 Guilarte Moreno, Verónica
A1 Fernández Rodríguez, Manuel A.
A1 García García, Patricia
A1 Hernando Santa Cruz, Elsa
A1 Sanz Díez, Roberto
K1 Química orgánica
K1 Chemistry, Organic
K1 Chemistry, Organic
AB An efficient synthesis of thiophenes and benzo[b]thiophenes has been developed from easily available bromoenynes and o-alkynylbromobenzene derivatives. This novel one-pot procedure involves a Pd-catalyzed C–S bond formation using a hydrogen sulfide surrogate followed by a heterocyclization reaction. Moreover, in situ functionalization with selected electrophiles further expands the potential of this methodology to the preparation of the corresponding highly substituted sulfur heterocycles.
PB American Chemical Society
SN 1523-7060
YR 2011
FD 2011-09
LK http://hdl.handle.net/10259/3909
UL http://hdl.handle.net/10259/3909
LA eng
NO Junta de Castilla y Leon (BU021A09 and GR-172) and Ministerio de Ciencia e Innovacion (MICINN) and FEDER (CTQ2010-15358 and CTQ2009-09949/BQU) for financial support. P.G.-G. and M.A.F.-R. thank MICINN for "Juan de la Cierva" and "Ramon y Cajal" contracts
DS Repositorio Institucional de la Universidad de Burgos
RD 23-nov-2024