RT info:eu-repo/semantics/article T1 Formulation and characterisation of wheat bran oil-in-water nanoemulsions A1 Rebolleda Alonso, Sara A1 Sanz Díez, Mª Teresa A1 Benito Moreno, José Manuel A1 Beltrán Calvo, Sagrario A1 Escudero Barbero, Isabel A1 González San José, Mª Luisa K1 Nanoemulsion K1 Wheat bran oil K1 Ultrasonication K1 Response surface methodology K1 Antioxidant capacity K1 Tyrosinase inhibition K1 Food K1 Chemical engineering K1 Alimentos K1 Ingeniería química AB Wheat bran oil (WBO) has been reported to have an important content of bioactive compounds, such astocopherols, alkylresorcinols, steryl ferulates and other phenolic compounds; however, its poor solubilityin water systems restricts its applications in the food industry. This study is focussed on the formulationof oil-in-water (O/W) nanoemulsions of WBO in order to improve the bioaccessibility of its active compounds.The influences of oil concentration, surfactant type and concentration, and emulsificationmethod, on the droplet size and stability of the nanoemulsions were investigated. Response surfacemethodology was used to optimise the conditions for preparing stable nanoemulsions with the minimumdroplet size. The optimal nanoemulsion was obtained when 1% of WBO and 7.3% of a surfactant mixtureof Span 80 (37.4%) and Tween 80 (62.6%) were emulsified in water by high intensity ultrasonication for50 s after pre-emulsification with a high speed blender during 5 min. The optimal nanoemulsion showedgood stability over time and antioxidant and tyrosinase inhibitory activities, which make it suitable foruse in food applications. PB Elsevier YR 2015 FD 2015-01 LK http://hdl.handle.net/10259/4343 UL http://hdl.handle.net/10259/4343 LA eng NO This work is part of the GALANG project (Ref.: ITC-20113029)financed by the Spanish Government through CDTI. DS Repositorio Institucional de la Universidad de Burgos RD 24-dic-2024