RT info:eu-repo/semantics/article
T1 Chemical speciation of MeHg+ and Hg2+ in aqueous solution and HEK cells nuclei by means of DNA interacting fluorogenic probes
A1 Díaz de Greñu Puertas, Borja
A1 García Calvo, José
A1 Cuevas Vicario, José Vicente
A1 García Herbosa, Gabriel
A1 García Ruiz, Begoña
A1 Busto Vázquez, Natalia
A1 Ibeas Cortes, Saturnino
A1 Torroba Pérez, Tomás
A1 Torroba, Blanca
A1 Herrera, Antonio
A1 Pons, Sebastian
K1 Chemistry, Organic
K1 Química orgánica
AB Selected new fluorogenic probes that interact in different ways with Hg2+ and MeHg+ have been preparedand used for the chemical speciation of both cations in aqueous solution as well as in HEK293 cells. The bestselective speciation of Hg2+ and MeHg+ has been achieved by in vitro approaches based on fluorogenicprobes supported in cultured cells, due to the particular sensitivity of the HEK293 cells to permeation byHg2+, MeHg+ and the fluorogenic probes. In particular, MeHg+ was selectively detected in cell nuclei byprobe JG45.
PB Royal Society of Chemistry
YR 2015
FD 2015-07
LK http://hdl.handle.net/10259/4361
UL http://hdl.handle.net/10259/4361
LA eng
NO the Ministeriode Econom´ıa y Competitividad, Spain (Projects CTQ2012-31611 and CTQ2014-58812-C2-2-R), Junta de Castilla y Le´on,Consejer´ıa de Educaci´on y Cultura y Fondo Social Europeo(Project BU246A12-1), Obra Social “la Caixa” OSLC-2012-007and the European Commission, Seventh Framework Programme(Project SNIFFER FP7-SEC-2012-312411).
DS Repositorio Institucional de la Universidad de Burgos
RD 25-nov-2024