RT info:eu-repo/semantics/article
T1 PTSA-Catalyzed Reaction of Indoles with 2-Oxoaldehydes: Synthesis of α,α-Bis(indol-3-yl) Ketones
A1 Suárez, Anisley
A1 Martínez Lara, Fernando
A1 Suárez Pantiga, Samuel
A1 Sanz Díez, Roberto
K1 Química orgánica
K1 Chemistry, Organic
AB A convenient procedure for accessing a,a-bis(indol-3-yl) ketonesfrom indoles and a-oxoaldehydes is described using aninexpensive and commercially available catalyst such as ptoluenesulfonicacid monohydrate. This protocol allows for thefirst time the synthesis of 2,2-bis(indolyl)-1-alkylethanones byemploying aliphatic 2-oxoaldehydes, even as aqueous solutions.The high-yielded obtained ketones have been shown asuseful starting materials for further synthetic transformations.
PB Wiley-VCH Verlag
SN 2365-6549
YR 2017
FD 2017-01
LK http://hdl.handle.net/10259/4529
UL http://hdl.handle.net/10259/4529
LA eng
NO Ministerio de Economía y Competitividad(MINECO) and FEDER (CTQ2013-48937-C2-1P) and Junta deCastilla y León and FEDER (BU076U16)
DS Repositorio Institucional de la Universidad de Burgos
RD 22-nov-2024