RT info:eu-repo/semantics/article T1 PTSA-Catalyzed Reaction of Indoles with 2-Oxoaldehydes: Synthesis of α,α-Bis(indol-3-yl) Ketones A1 Suárez, Anisley A1 Martínez Lara, Fernando A1 Suarez Pantiga, Samuel A1 Sanz Díez, Roberto K1 Química orgánica K1 Chemistry, Organic AB A convenient procedure for accessing a,a-bis(indol-3-yl) ketonesfrom indoles and a-oxoaldehydes is described using aninexpensive and commercially available catalyst such as ptoluenesulfonicacid monohydrate. This protocol allows for thefirst time the synthesis of 2,2-bis(indolyl)-1-alkylethanones byemploying aliphatic 2-oxoaldehydes, even as aqueous solutions.The high-yielded obtained ketones have been shown asuseful starting materials for further synthetic transformations. PB Wiley-VCH Verlag SN 2365-6549 YR 2017 FD 2017-01 LK http://hdl.handle.net/10259/4529 UL http://hdl.handle.net/10259/4529 LA eng NO Ministerio de Economía y Competitividad(MINECO) and FEDER (CTQ2013-48937-C2-1P) and Junta deCastilla y León and FEDER (BU076U16) DS Repositorio Institucional de la Universidad de Burgos RD 28-mar-2024