RT info:eu-repo/semantics/article
T1 Molybdenum-Catalyzed Synthesis of Nitrogenated Polyheterocycles from Nitroarenes and Glycols with Reuse of Waste Reduction By-product
A1 Rubio Presa, Rubén
A1 Pedrosa Sáez, María de los Remedios
A1 Fernández Rodríguez, Manuel A.
A1 Arnáiz García, Francisco Javier
A1 Sanz Díez, Roberto
K1 Química orgánica
K1 Chemistry, Organic
AB A novel domino reduction/imine formation/intramolecular cyclization/oxidation for the efficient synthesis of pyrrolo(indolo)[1,2-a]quinoxalines and pyrrolo(indolo)[3,2-c]-quinolines from readily available nitrobenzenes and glycols is reported. The process utilizes the carbonyl byproduct of the initial dioxomolybdenum(VI)-catalyzed reduction of nitroaromatics with glycols as a reagent for the imine generation. This method represents the first sustainable domino reaction for the preparation of biologically relevant heterocycles that internally incorporates the waste formed in the first step to the final product.
PB American Chemical Society
SN 1523-7060
YR 2017
FD 2017-10
LK http://hdl.handle.net/10259/4924
UL http://hdl.handle.net/10259/4924
LA eng
NO Junta de Castilla y León and FEDER(BU076U16) and Ministerio de Economíay Competitividad(MINECO) (CTQ2015-70371-REDT and CTQ2016-75023-C2-1-P)
DS Repositorio Institucional de la Universidad de Burgos
RD 11-dic-2024