RT info:eu-repo/semantics/article T1 Molybdenum-Catalyzed Synthesis of Nitrogenated Polyheterocycles from Nitroarenes and Glycols with Reuse of Waste Reduction By-product A1 Rubio Presa, Rubén A1 Pedrosa Sáez, María de los Remedios A1 Fernández Rodríguez, Manuel A. A1 Arnáiz García, Francisco Javier A1 Sanz Díez, Roberto K1 Química orgánica K1 Chemistry, Organic AB A novel domino reduction/imine formation/intramolecular cyclization/oxidation for the efficient synthesis of pyrrolo(indolo)[1,2-a]quinoxalines and pyrrolo(indolo)[3,2-c]-quinolines from readily available nitrobenzenes and glycols is reported. The process utilizes the carbonyl byproduct of the initial dioxomolybdenum(VI)-catalyzed reduction of nitroaromatics with glycols as a reagent for the imine generation. This method represents the first sustainable domino reaction for the preparation of biologically relevant heterocycles that internally incorporates the waste formed in the first step to the final product. PB American Chemical Society SN 1523-7060 YR 2017 FD 2017-10 LK http://hdl.handle.net/10259/4924 UL http://hdl.handle.net/10259/4924 LA eng NO Junta de Castilla y León and FEDER(BU076U16) and Ministerio de Economíay Competitividad(MINECO) (CTQ2015-70371-REDT and CTQ2016-75023-C2-1-P) DS Repositorio Institucional de la Universidad de Burgos RD 29-mar-2024