RT info:eu-repo/semantics/article T1 Kinetic models of migration of melamine and formaldehyde from melamine kitchenware with data of liquid chromatography A1 Arce Antón, Mar A1 Sanllorente Méndez, Silvia A1 Ortiz Fernández, Mª Cruz K1 Melamine K1 Formaldehyde K1 Kitchenware K1 HPLC-DAD K1 Migration kinetic curve K1 Specific migration limit K1 Química analítica K1 Chemistry, Analytic AB European legislation has established a specific migration limit (SML) of 15 mg kg−1 for formaldehyde and 2.5 mg kg−1 for melamine. Formaldehyde resins are used in the manufacture of melamine kitchenware. Formaldehyde is listed in group 1 of the IARC list of carcinogenic compounds. To determine the quantity of formaldehyde and melamine as potential migrants from different types of melamine kitchenware (glass, mug, cutlery, big cup and bowl), a HPLC-DAD method has been implemented. This method is an alternative to the ones proposed in technical guidelines to determine formaldehyde by UV–vis spectrophotometry and melamine by HPLC. The final objective was to fit the migration kinetic curves of these two analytes in melamine kitchenware.After the method was validated, decision limit (CCα) and detection capability (CCβ) were calculated for both analytes, when the probabilities of false positive (α) and false negative (β) were fixed at 0.05; being CCβ 0.269 mg L−1 and 0.311 mg L−1 for melamine and formaldehyde respectively. CCα and CCβ were also calculated at the SML of both analytes.The migration testing were conducted with simulant B (3% acetic acid (w/v) in aqueous solution), the conditions of each exposure being 70 °C for 2 h. The quantities of melamine and formaldehyde found in the third exposure of the total kitchenware analysed were between 0.21 and 1.09 mg L−1 and between 0.55 and 3.86 mg L−1, respectively.Migration kinetic curves were built for each type of kitchenware with the data of sixteen consecutive migration cycles (70 °C each 30 min). The SML for melamine was surpassed in the mug, in the big cup and in the bowl after eleven, thirteen and one cycles, respectively.When more cycles were carried out in the mug, the values of the accumulated quantity of formaldehyde and melamine were 15.30 and 6.79 mg L−1, respectively, after thirty-two cycles. Both concentrations exceeded the corresponding SML. PB Elsevier SN 0021-9673 YR 2019 FD 2019-08 LK http://hdl.handle.net/10259/5118 UL http://hdl.handle.net/10259/5118 LA eng NO MINECO (AEI/FEDER, UE) and Consejería de Educación de la Junta de Castilla y León through projects CTQ2017-88894-R and BU012P17 respectively (all co-financed with FEDER funds) DS Repositorio Institucional de la Universidad de Burgos RD 25-abr-2024