RT info:eu-repo/semantics/article
T1 Gold(i)-catalyzed nucleophilic cyclization of β-monosubstituted o-(alkynyl)styrenes: a combined experimental and computational study
A1 Virumbrales Ortiz, Cintia
A1 Solas Luera, Marta
A1 Suarez Pantiga, Samuel
A1 Fernández Rodríguez, Manuel A.
A1 Marín Luna, Marta
A1 Silva López, Carlos
A1 Sanz Díez, Roberto
K1 Química orgánica
K1 Chemistry, Organic
AB The stereospecific gold(I)-catalyzed nucleophilic cyclization of β-monosubstituted o-(alkynyl)styrenes to produce C-1 functionalized 1H-indenes including challenging substrates and nucleophiles, such as β-(cyclo)alkyl-substituted o-(alkynyl)styrenes and a variety of alcohols as well as selected electron-rich aromatics, is reported. DFT calculations support the stereochemical outcome of the process that involves the formation of a key cyclopropyl gold carbene intermediate through a regiospecific 5-endo cyclization.
PB Royal Society of Chemistry
SN 1477-0520
YR 2019
FD 2019-12
LK http://hdl.handle.net/10259/5213
UL http://hdl.handle.net/10259/5213
LA eng
NO Ministerio de Economía y Competitividad (MINECO) and FEDER (CTQ2016-75023-C2-1-P and 2-P), and Junta de Castilla y León and FEDER (BU291P18) and Xunta de Galicia (ED431C 2017/70 and ED431E 2018/07)
DS Repositorio Institucional de la Universidad de Burgos
RD 19-abr-2024