RT info:eu-repo/semantics/article T1 Sensor system based on flexible screen-printed electrodes for electrochemical detection of okadaic acid in seawater A1 Molinero Abad, Begoña A1 Pérez Ruiz, Lydia A1 Izquierdo Bote, Daniel A1 Escudero Barbero, Isabel A1 Arcos Martínez, Julia K1 Okadaic acid K1 Screen printed electrodes K1 Textile sensors K1 Seawater K1 PP2A K1 Química analítica K1 Chemistry, Analytic AB The monitoring of marine dinophysistoxin okadaic acid in seawater can serve as an early alert system for preventing the potential negative effects this toxin can have on the food industry and human health in general. A disposable sensor system for electrochemical detection of this toxin has been developed using screen-printed electrodes. The method described is based on the inhibition of protein phosphatase type 2A by okadaic acid, evaluating the enzyme activity. p-Nitrophenyl phosphate, 4-methylumbelliferyl phosphate and phenyl phosphate have been tested as substrates achieving good limits of detection of 2.7·10–12 M of okadaic acid. The proposed method has been successfully applied to okadaic acid determination in seawater samples. A study of divalent cations present in seawater that can interfere with the measurement has been carried out. The electrode systems were printed on both rigid and textile backing materials to observe the influence of those materials on the final performance of the sensor. PB Elsevier SN 0039-9140 YR 2019 FD 2019-01 LK http://hdl.handle.net/10259/5345 UL http://hdl.handle.net/10259/5345 LA eng NO Ministerio de Ciencia e Innovación (MICINN) (TEC2013-405661-P) Ministerio de Economía y Competitividad (MINECO) and European Regional Development Fund (FEDER) (MUSSEL RTC-2015-4077-2). DS Repositorio Institucional de la Universidad de Burgos RD 21-nov-2024