RT info:eu-repo/semantics/article
T1 Evaluation of bioactive compounds and biological activities of Tunisian propolis
A1 Gargouri, Wafa
A1 Osés Gómez, Sandra María
A1 Fernández Muiño, Miguel Ángel
A1 Sancho Ortiz, María Teresa
A1 Kechaou, Nabil
K1 Propolis
K1 Phenolics
K1 HPLC-UV
K1 Antioxidant activity
K1 ACE
K1 Alimentos
K1 Food
AB The aim of this study was to investigate the phytochemical composition and biological properties of Tunisian propolis from four different regions: Kasserine, Béja, Kèf and Monastir. Ethanolic extracts of propolis were prepared using two extraction methods; solvent and ultrasonic extraction. Total phenolics, flavonoids, ABTS free radical and hydroxyl radicals scavenging abilities, anti-inflammatory, anti-hypertensive, as well as antimicrobial activities of propolis extracts were determined. Identification and quantification of phenolic and flavonoid compounds were performed by using both HPLC-UV and HPLC-ESI-MS. The results revealed high contents of total phenolics and flavonoids and polyphenols extraction was more efficient by sonication. Caffeic acid phenethyl ester (CAPE), galangin, and genistein were the major identified compounds. Antihypertensive activity, evaluated in propolis extracts for first time by HPLC-UV, was higher than 90% for all extracts. Tunisian propolis is an important natural source of polyphenols and flavonoids. The best extraction method was ultrasonic for antioxidants and most of biological activities; conventional method seems to be more suitable for anti-inflammatory activity. Propolis from Béja contains the highest amount of antioxidants and have a stronger potential biological activities. Tunisian propolis could be, therefore, a promising raw material for food and pharmaceutical industry.
PB Elsevier
SN 0023-6438
YR 2019
FD 2019-08
LK http://hdl.handle.net/10259/5365
UL http://hdl.handle.net/10259/5365
LA eng
DS Repositorio Institucional de la Universidad de Burgos
RD 23-nov-2024