RT info:eu-repo/semantics/article
T1 Phenolic Profile, Antioxidant Capacities and Enzymatic Inhibitory Activities of Propolis from Different Geographical Areas: Needs for Analytical Harmonization
A1 Osés Gómez, Sandra María
A1 Marcos, Patricia
A1 Azofra, Patricia
A1 Pablo, Ana de
A1 Fernández Muiño, Miguel Ángel
A1 Sancho Ortiz, María Teresa
K1 propolis
K1 phenolic profile
K1 antioxidant capacities
K1 hyaluronidase inhibitory activity
K1 ACE inhibitory activity
K1 Alimentos
K1 Food
AB Propolis is a resinous vegetal exudate modified by bees, and is interesting as apreservative and potentially functional product. This work dealt with studying the commonphenolic profiles and antioxidant capacities of 13 bee propolis from different geographical areas.Both hyaluronidase and angiotensin converting enzyme (ACE) inhibitory activities were alsoassessed and related when possible with particular phenolic compounds. High performance liquidchromatography‐ultraviolet detection (HPLC‐UV) analysis showed that every propolis containedp‐coumaric acid (1.2–12.2 mg/g) and ferulic acid (0.3–11.0 mg/g). Pinocembrin, catechin, and caffeicacid phenethyl ester (CAPE) plus galangin were the main flavonoids. Antioxidant activities werehigher than 280 μmol trolox/g for trolox equivalent antioxidant capacity (TEAC), 0.099 mmol uricacid/g for radical‐scavenging effect on hydroxyl radicals, and 0.19 mg/mL for half maximalinhibitory concentration (IC50) of antioxidant activity against superoxide anion radical. Workingwith solutions of 10 mg/mL propolis, hyaluronidase inhibitory activity ranged between 0% and68.20%, being correlated to ferulic acid content. ACE inhibitory effect determined by HPLC washigher than 78%, being correlated with catechin and p‐coumaric acid. Therefore, propolis could beuseful for food, pharmaceutical, and cosmetic companies, also helping to reduce risk factors fordiseases related to oxidative damage, inflammatory processes, and hypertension. This research alsohighlights the necessity for harmonized analysis methods and the expression of results for propolis.
PB MDPI
YR 2020
FD 2020-01
LK http://hdl.handle.net/10259/5367
UL http://hdl.handle.net/10259/5367
LA eng
DS Repositorio Institucional de la Universidad de Burgos
RD 26-abr-2024