RT info:eu-repo/semantics/article
T1 The dose–response effect on polyphenol bioavailability after intake of white and red wine pomace products by Wistar rats
A1 Gerardi, Gisela
A1 Cavia Saiz, Mónica
A1 Rivero Pérez, Maria Dolores
A1 González San José, Mª Luisa
A1 Muñiz Rodríguez, Pilar
K1 Alimentos
K1 Food
AB Wine pomace by-products are an important source of phenolic acids with significant health benefits. However, phenolic acid bioavailability in vivo has been little studied and there are few comparative studies on bioavailability between red and white wine pomace and the effect of intake of different doses. The qualitative and quantitative profile of phenolic acid metabolites in plasma and urine samples from Wistar rats was obtained by gas chromatography/mass detection, after oral administration of four doses (50, 100, 150, and 300 mg) of both the red and the white wine pomace products (rWPP and wWPP, respectively). The antioxidant capacity of the plasma samples assessed by both the ABTS and the FRAP levels was also evaluated. The results showed that neither the bioavailability nor the antioxidant capacity in vivo of the rWPP increased at high doses. However, both parameters were dependent on the intake of the wWPP.
PB Royal Society of Chemistry
SN 2042-6496
YR 2020
FD 2020-02
LK http://hdl.handle.net/10259/5462
UL http://hdl.handle.net/10259/5462
LA eng
NO Ministry of Science, Innovation and Universities (Research project PGC2018-097113-B-I00)
DS Repositorio Institucional de la Universidad de Burgos
RD 25-dic-2024