RT info:eu-repo/semantics/article
T1 Toxicological evaluation of MnAl based permanent magnets using different in vitro models
A1 Rumbo Lorenzo, Carlos
A1 Cancho Espina, Cristina
A1 Popov, Vladimir V.
A1 Skokov, Konstantin
A1 Tamayo Ramos, Juan Antonio
K1 Magnetic alloys
K1 Toxicity assays
K1 Cell lines
K1 Yeast
K1 Bacteria
K1 Química orgánica
K1 Chemistry, Organic
AB Due to economic, environmental and geopolitical issues, the development of permanent magnets with a composition free of rare earth elements and with acceptable magnetic properties has been considered a priority by the international community, being MnAl based alloys amongst the most promising candidates. The aim of this work was to evaluate the toxicity of powders of two forms of newly developed MnAl(C) permanent magnets through exposure experiments applying three model organisms, using as a benchmark powders of a commercial rare-earth-containing magnet (Nd2Fe14B). For this purpose, the direct exposure to the different particles suspensions as well as to magnets leachates was evaluated. Both viability and oxidative stress assays were applied in an adenocarcinomic human alveolar basal epithelial cell line (A549) and in the yeast Saccharomyces cerevisiae, together with the bioluminescent inhibition assay in the Gram negative bacterium Vibrio fischeri. The obtained results indicate that MnAl(C) permanent magnets, in general terms, presented similar toxicity than the Nd magnet for the selected biological models under the studied conditions. Overall, the presented data provide, for the first time, an in vitro toxicity analysis of MnAl based magnets.
PB Elsevier
SN 0045-6535
YR 2021
FD 2021-01
LK http://hdl.handle.net/10259/5518
UL http://hdl.handle.net/10259/5518
LA eng
NO European Union’s Horizon 2020 NOVAMAG project (NMBP 23-2015, grant agreement N  686056) and from the Junta de Castilla y Leon and the European Social Fund-Youth European Initiative grant UBU-15-A.
DS Repositorio Institucional de la Universidad de Burgos
RD 23-nov-2024