RT info:eu-repo/semantics/article T1 A Flexible Platform of Electrochemically Functionalized Carbon Nanotubes for NADH Sensors A1 Heras Vidaurre, Aránzazu A1 Vulcano, Fabio A1 Garoz Ruiz, Jesús A1 Porcelli, Nicola A1 Terzi, Fabio A1 Colina Santamaría, Álvaro A1 Seeber, Renato A1 Zanardi, Chiara K1 Single-walled carbon nanotubes K1 Caffeic acid K1 Catechol K1 NADH oxidation K1 Electrocatalysis K1 Amperometric sensor K1 Voltabsorptometric sensor K1 Spectroelectrochemistry K1 Química analítica K1 Chemistry, Analytic AB A flexible electrode system entirely constituted by single-walled carbon nanotubes(SWCNTs) has been proposed as the sensor platform for -nicotinamide adenine dinucleotide(NADH) detection. The performance of the device, in terms of potential at which the electrochemicalprocess takes place, significantly improves by electrochemical functionalization of the carbon-basedmaterial with a molecule possessing an o-hydroquinone residue, namely caffeic acid. Both theprocesses of SWCNT functionalization and NADH detection have been studied by combiningelectrochemical and spectroelectrochemical experiments, in order to achieve direct evidence of theelectrode modification by the organic residues and to study the electrocatalytic activity of the resultingmaterial in respect to functional groups present at the electrode/solution interface. Electrochemicalmeasurements performed at the fixed potential of +0.30 V let us envision the possible use of thedevice as an amperometric sensor for NADH detection. Spectroelectrochemistry also demonstratesthe effectiveness of the device in acting as a voltabsorptometric sensor for the detection of this sameanalyte by exploiting this different transduction mechanism, potentially less prone to the possiblepresence of interfering species. PB MDPI SN 1424-8220 YR 2019 FD 2019-02 LK http://hdl.handle.net/10259/6120 UL http://hdl.handle.net/10259/6120 LA eng NO FEDER and both the Spanish Ministerio de Economía y Competitividad (Grants CTQ2017-83935-R-AEI/FEDER-UE) and the Consejería de Educación -Junta de Castilla y León- (Grant BU297P18). Jesus Garoz-Ruiz thanks Ministerio de Economía y Competitividad for his postdoctoral contracts (CTQ2014-55583-R; CTQ2017-83935-R AEI/FEDER-UE). Fabio Vulcano thanks the ISOF institute of CNR for supporting his PhD Grant. Nicola Porcelli thanks Università di Modena e Reggio Emilia for supporting his stay at the University of Burgos. DS Repositorio Institucional de la Universidad de Burgos RD 28-mar-2024