RT info:eu-repo/semantics/article
T1 Electrochemical generation of surface enhanced Raman scattering substrates for the determination of folic acid
A1 Cheuquepan Valenzuela, William
A1 Hernández Muñoz, Sheila
A1 Pérez Estébanez, Martín
A1 Romay, L.
A1 Heras Vidaurre, Aránzazu
A1 Colina Santamaría, Álvaro
K1 Spectroelectrochemistry
K1 Surface enhanced Raman Scattering
K1 SERS
K1 RAMAN
K1 Química analítica
K1 Chemistry, Analytic
AB Electrochemistry is a very useful technique to generate surface enhanced Raman scattering (SERS) substrates. SERS depends on two mechanisms: the electromagnetic effect, related to the plasmonic properties of the nanostructures in the substrate, and the chemical mechanism, related to the interaction between the target molecule and the substrate. Thus, Raman enhancement for a molecule strongly depends on the nature of the nanostructures that form the substrate. In this work, time-resolved Raman spectroelectrochemistry is used to generate SERS substrates, obtaining the Raman signal during the generation of the substrate, which is very useful to obtain valuable information on the Raman performance of the substrate. Two metals, Au and Ag, have been used to determine folic acid in a drug. In this example, Au SERS substrates are highly influenced by interfering compounds present in the drug tables. On the contrary, Ag SERS substrates have been demonstrated to yield very good figures of merit in the determination of folic acid in this complex sample.
PB Elsevier
SN 1572-6657
YR 2021
FD 2021-09
LK http://hdl.handle.net/10259/6128
UL http://hdl.handle.net/10259/6128
LA spa
NO Ministerio de Economía, y Competitividad (Grant CTQ2017-83935-R-AEI/FEDERUE), Junta de Castilla y León (Grant BU297P18) and Ministerio de Ciencia, Innovación y Universidades (Grant RED2018-102412-T). W. Ch. thanks JCyL for his postdoctoral fellowship (Grant BU297P18).
DS Repositorio Institucional de la Universidad de Burgos
RD 23-nov-2024