RT info:eu-repo/semantics/article
T1 Double fingerprint characterization of uracil and 5-fluorouracil
A1 Pérez Estébanez, Martín
A1 Cheuquepan Valenzuela, William
A1 Cuevas Vicario, José Vicente
A1 Hernández Muñoz, Sheila
A1 Heras Vidaurre, Aránzazu
A1 Colina Santamaría, Álvaro
K1 Spectroelectrochemistry
K1 Raman
K1 EC-SERS
K1 EC-SOERS
K1 Química analítica
K1 Chemistry, Analytic
AB Time Resolved Raman spectroelectrochemistry (TR-Raman-SEC) has been used for the first time to obtain two different Raman spectra of one single analyte in the same experiment. This double detection has been accomplished thanks to the use of electrochemical surface enhanced Raman scattering (EC-SERS) and electrochemical surface oxidation enhanced Raman scattering (EC-SOERS) in the same experiment. These two Raman enhancement phenomena can provide a broad insight into the interaction between analyte and substrate surface when they are combined. To prove the possibilities of this methodology, a Raman spectroelectrochemistry study of uracil (U) and 5-fluorouracil (5-FU), two analytes with relevance in medicine and biochemistry, have been performed. Density functional theory (DFT) calculations has been carried out to shed more light on the interaction of these molecules with silver substrates in acidic media.
PB Elsevier
SN 0013-4686
YR 2021
FD 2021-08
LK http://hdl.handle.net/10259/6129
UL http://hdl.handle.net/10259/6129
LA spa
NO Ministerio de Economía, y Competitividad (Grant CTQ2017–83935-R-AEI/FEDERUE), Junta de Castilla y León (Grant BU297P18, Grant BU087G19, and Grant BU263P18) and Ministerio de Ciencia, Innovación y Universidades (Grant RED2018–102412-T and Grant PID2019–111215RB-I00). W. Ch. thanks JCyL for his postdoctoral fellowship (Grant BU297P18). S.H. thanks JCyL and European Social Fund for her predoctoral fellowship. M.P-E. thanks JCyL, the European Social Fund and the Youth Employment initiative and JCyL and European Social Fund for his predoctoral fellowship. This research has made use of the high-performance computing resources of the Castilla y León Supercomputing Center (SCAYLE, https://www.scayle.es), financed by FEDER (Fondo Europeo de Desarrollo Regional). Jorge Gonzalez is acknowledged for his help in the laboratory whose contract was founded by JCyL, the European Social Fund and the Youth Employment Initiative.
DS Repositorio Institucional de la Universidad de Burgos
RD 11-dic-2024