RT info:eu-repo/semantics/article
T1 Determination of nicotinamide in a multivitamin complex by electrochemical-surface enhanced Raman spectroscopy
A1 Hernández Muñoz, Sheila
A1 Perales Rondon, Juan Víctor
A1 Arnaiz, Alvaro
A1 Pérez Estébanez, Martín
A1 Gomez, Elvira
A1 Colina Santamaría, Álvaro
A1 Heras Vidaurre, Aránzazu
K1 Spectroelectrochemistry
K1 Vitamin B3
K1 EC-SERS
K1 Raman spectroscopy
K1 Standard addition method
K1 Química analítica
K1 Chemistry, Analytic
AB Time resolved Raman spectroelectrochemistry is a powerful technique to prepare useful Surface Enhanced Raman Scattering (SERS) substrates suitable for quantitative analysis. Moreover, following the evolution of the Raman signal with the applied potential the selection of the best conditions for the analysis is quite simple. In this work, gold SERS substrates are prepared on screen-printed electrodes for the determination of nicotinamide, vitamin B3, in a multivitamin complex. The formation of the substrate has been monitored using UV/Vis absorption spectroelectrochemistry and scanning electron microscopy, which confirmed the generation of gold nanoparticles on the electrode surface. This new method has demonstrated to be suitable for the direct quantification of simple test samples using small sample volumes (50 μL). However, it failed when a complex sample, containing several interfering species, was analysed. A high interference on the preparation of the SERS substrate is observed during the analysis of a multivitamin complex. Despite that, nicotinamide was selectively determined in a multivitamin complex using the method of the standard addition, obtaining remarkable figures of merit (R2 = 0.99, %RSD < 9%).
PB Elsevier
SN 1572-6657
YR 2020
FD 2020-12
LK http://hdl.handle.net/10259/6130
UL http://hdl.handle.net/10259/6130
LA spa
NO Ministerio de Economía, y Competitividad (Grant CTQ2017-83935-R-AEI/FEDERUE), Junta de Castilla y León (Grant BU297P18) and Ministerio de Ciencia, Innovación y Universidades (Grant RED2018-102412-T). J.V.P-R. thanks Junta de Castilla y León for his postdoctoral fellowship (Grant BU033-U16)
DS Repositorio Institucional de la Universidad de Burgos
RD 25-dic-2024