RT info:eu-repo/semantics/article
T1 Asymmetric Gold(I)‐Catalyzed Tandem Hydroarylation–Nazarov Cyclization: Enantioselective Access to Cyclopentenones
A1 Solas Luera, Marta
A1 Suarez Pantiga, Samuel
A1 Sanz Díez, Roberto
K1 Asynmetric Catalysis
K1 Cyclopentenones
K1 Gold
K1 Hydroarylation
K1 Nazarov Cyclization
K1 Química orgánica
K1 Chemistry, Organic
AB The asymmetric synthesis of cyclopentachromenones from gold-catalyzed reaction of readily available skipped alkenynones is described. This cascadereaction involves an initial anti-Michael hydroarylationof the ynone moiety to form a gold-functionalizeddialkenylketone intermediate, followed by a Nazarovcyclization that proceeds in an unprecedented enantioselective manner. Excellent enantiomeric ratios and chemical yields are obtained under mild reaction conditions.
PB Wiley
SN 1433-7851
YR 2022
FD 2022
LK http://hdl.handle.net/10259/7412
UL http://hdl.handle.net/10259/7412
LA eng
NO We gratefully acknowledge Ministerio de Ciencia e Innovación and FEDER (CTQ2016-75023-C2-1-P and PID2020- 115789GB-C21), and Junta de Castilla y León and FEDER (BU291P18 and BU049P20) for financial support. The project leading to these results has received funding from “la Caixa” Foundation, under the Agreement LCF/PR/ PR18/51130007> (CAIXA-UBU001). M.S. and S.S.-P. thank Junta de Castilla y León (Consejería de Educación) and Fondo Social Europeo (ESF+) for a predoctoral and a postdoctoral contract, respectively.
DS Repositorio Institucional de la Universidad de Burgos
RD 02-may-2024