RT info:eu-repo/semantics/article
T1 Synthesis of water-soluble hemicoronenediimides by photocyclization of perylenediimides: Turn-on fluorescent probes in water by complexation with Cucurbit[7]uril or binding to G-quadruplex Motifs
A1 Busto Vázquez, Natalia
A1 Romero Velásquez, Daisy Carolina
A1 Revilla Cuesta, Andrea
A1 Abajo Cuadrado, Irene
A1 Cuevas Vicario, José Vicente
A1 Rodríguez Rodríguez, Mª Teresa
A1 García Ruiz, Begoña
A1 Torroba Pérez, Tomás
K1 Perylenediimides
K1 Hemicoronenediimides
K1 Photocyclization
K1 Nanoparticles
K1 G-quadruplex
K1 Cucurbituril
K1 Cytotoxicity
K1 Salud
K1 Health
K1 Fisiología
K1 Physiology
K1 Química orgánica
K1 Chemistry, Organic
AB A new series of perylene and hemicoronene diimides, obtained by visible light photocyclization, are presented,between them some remarkable examples that are soluble in only water, and give nanoparticles by selfassociation. Those compounds work as new fluorescent materials in water by complexation with cucurbit[7]uril, as well as selective G-quadruplex binding ligands with remarkable cytotoxic activity when the interactionwith G4 was sufficiently strong.
PB Elsevier
SN 0143-7208
YR 2022
FD 2022-09
LK http://hdl.handle.net/10259/7496
UL http://hdl.handle.net/10259/7496
LA eng
NO We acknowledge the Ministerio de Ciencia, Innovación y Universidades-FEDER (Grants PID2019-111215RB-100 and RTI2018- 102040-B-100), the Junta de Castilla y León, Consejería de Educación y Cultura y Fondo Social Europeo (Grants BU263P18 and BU305P18), “la Caixa” Foundation (LCF/PR/PR12/11070003) for financial support. A. R.C. thanks Secretaría General de Universidades for a FPU18/03225 Grant. This research has made use of the high-performance computing resources of the Castilla y León Supercomputing Center (SCAYLE, htt ps://www.scayle.es), financed by FEDER (Fondo Europeo de Desarrollo Regional). We thank Ms. Ma del Pilar Castroviejo-Fernández, from PCT, UBU, for assistance in AFM studies and Mr. Javier Gutierrez-Reguera from LTI, UVA, for assistance in DLS studies.
DS Repositorio Institucional de la Universidad de Burgos
RD 04-dic-2024