RT info:eu-repo/semantics/article T1 Effects of Antioxidants on Pain Perception in Patients with Fibromyalgia—A Systematic Review A1 Fernández-Araque, Ana A1 Verde, Zoraida A1 Torres-Ortega, Clara A1 Sainz-Gil, María A1 Velasco-González, Verónica A1 González Bernal, Jerónimo A1 Mielgo Ayuso, Juan K1 Antioxidants K1 Fibromyalgia K1 Pain K1 Supplementation K1 Systematic review K1 Fisiología K1 Physiology K1 Psicología K1 Psychology K1 Salud K1 Health AB In recent years, antioxidant supplements have become popular to counteract the effectsof oxidative stress in fibromyalgia and one of its most distressing symptoms, pain. The aim ofthis systematic review was to summarize the effects of antioxidant supplementation on pain levelsperceived by patients diagnosed with fibromyalgia. The words used respected the medical searchterms related to our objective including antioxidants, fibromyalgia, pain, and supplementation.Seventeen relevant articles were identified within Medline (PubMed), Scopus, Web of Science (WOS),the Cochrane Database of Systematic Review, and the Cochrane Central Register of Controlled Trials.This review found that antioxidant supplementation is efficient in reducing pain in nine of the studiesreviewed. Studies with a duration of supplementation of at least 6 weeks showed a benefit on painperception in 80% of the patients included in these studies. The benefits shown by vitamins andcoenzyme Q10 are remarkable. Further research is needed to identify the effects of other types ofantioxidants, such as extra virgin olive oil and turmeric. More homogeneous interventions in termsof antioxidant doses administered and duration would allow the effects on pain to be addressed morecomprehensively. PB MDPI YR 2022 FD 2022-04 LK http://hdl.handle.net/10259/7610 UL http://hdl.handle.net/10259/7610 LA eng DS Repositorio Institucional de la Universidad de Burgos RD 20-abr-2024