RT info:eu-repo/semantics/conferenceObject T1 Parameter fitting in models of biofilm resistance to antibiotics A1 Cebrián de Barrio, Elena A1 Carpio, Ana K1 Microbiología K1 Microbiology K1 Matemáticas K1 Mathematics AB Biofilms are communities formed by bacteria attached to surfaces and protected from antibiotic attacks by a polymeric matrix (EPS). Dynamic Energy Budget (DEB) models take into account the diversity of the mechanisms involved in biofilm resistance to antibiotics and allow us to study their effects on bacteria. These models involve sets of unknown parameters, which must be fitted to experimental data in such a way that the model predictions are consistent with experiments. Varying these parameters in a simplified model, we are able to calibrate their values and understand their influence on different bacterial distributions. PB American Institute of Physics SN 0094-243X YR 2018 FD 2018 LK http://hdl.handle.net/10259/8273 UL http://hdl.handle.net/10259/8273 LA eng NO Research partially supported by MINECO grant No. MTM2014-56948-C2-1-P. DS Repositorio Institucional de la Universidad de Burgos RD 21-nov-2024