RT info:eu-repo/semantics/article T1 Validation of screening instruments for neuroepidemiological surveys of tic disorders A1 Cubo Delgado, Esther A1 Sáez Velasco, Sara A1 Delgado Benito, Vanesa A1 Ausín Villaverde, Vanesa A1 Trejo Gabriel y Galán, José Mª A1 Martín Santidrián, Asunción A1 Macarrón Vicente, Jesus A1 Cordero Guevara, José A1 Louis, Elan D. A1 Benito-León, Julián K1 Tics K1 Screening K1 Telephone-based interview K1 School samples K1 Neurología K1 Neurology K1 Psicología K1 Psychology K1 Salud K1 Health K1 Sistema nervioso-Enfermedades K1 Nervous system-Diseases AB Background:The main purpose was to validate a multistage protocol to screen tic disorders in mainstream and special education centers and to investigate whether telephone-based interviews were accurate to diagnose tic disorders when compared with in-person neurological interviews.Methods:A school-based survey of children and adolescents (6–16 years). A proxy report questionnaire for tic disorders was completed by teachers, observers, and parents. The diagnosis was confirmed by the neurologist based on the Diagnostic and Statistical Manual of Mental disorders (DSM-IV TR) criteria. The sensitivity, specificity, positive and negative predictive values, the likelihood ratio for a positive result (LR+), and the Kappa coefficients (k) for telephone-based interviews reliability were calculated.Results:One hundred twenty subjects, 57 from special education center and 63 from a mainstream school were studied. The sensitivity of the proxy report questionnaire was 58% and 36% when completed by the observers (mainstream and special education center, respectively), 40 and 73% when completed by the teachers, and 58 and 36% when completed by the parents. Using any of these 3 screening sources, the sensitivity was 92%, the positive predictive value was 38%, and negative predictive value was 97% (mainstream schools), whereas the sensitivity was 82%, the positive predictive value was 20%, and negative predictive value was 82% (special education centers). Parents (mainstream schools) and teachers (special education center) produced the highest LR+ (7.25 and 1.26, respectively) and the intraobserver reliability of the telephone-based interviews versus in-person neurological interviews gave a k coefficient of 0.83.Conclusions:The efficiency of different screening instruments for tic disorders seems to vary in different settings. Telephone-based interviews may be a valid and convenient backup to ascertain the diagnosis of tic disorders when face-to-face neurological examination is not possible. PB Wiley SN 0885-3185 YR 2011 FD 2011 LK http://hdl.handle.net/10259/8378 UL http://hdl.handle.net/10259/8378 LA eng DS Repositorio Institucional de la Universidad de Burgos RD 08-may-2024