RT info:eu-repo/semantics/article
T1 Effects of home-based mirror therapy and cognitive therapeutic exercise on the improvement of the upper extremity functions in patients with severe hemiparesis after a stroke: a protocol for a pilot randomised clinical trial
A1 González Santos, Josefa
A1 Soto Cámara, Raúl
A1 Rodríguez Fernández, Paula
A1 Jiménez Barrios, María
A1 González Bernal, Jerónimo
A1 Collazo Riobó, Carla
A1 Jahouh, Maha
A1 Bravo-Anguiano, Yolanda
A1 Trejo Gabriel y Galán, José Mª
K1 Psicología
K1 Psychology
K1 Terapéutica
K1 Therapeutics
K1 Salud
K1 Health
K1 Sistema nervioso-Enfermedades
K1 Nervous system-Diseases
AB Introduction Neuroplasticity is defined as the capacity of the brain to reorganise new neuronal pathways. Mirror therapy (MT) and cognitive therapeutic exercise (CTE) are two neurorehabilitation techniques based on neuroplasticity and designed to improve the motor functions of the affected upper extremity in patients with severe hemiparesis after a stroke. Home-based interventions are an appropriate alternative to promote independence and autonomy. The objective of this study is to evaluate which of these techniques, MT and CTE, combined with task-oriented training, is more effective in functional recovery and movement patterns of the upper extremities in patients with severe hemiparesis after a stroke.Methods and analysis This is a home-based, single-blind, controlled, randomised clinical trial with three parallel arms, including 154 patients who had a stroke aged above 18 years. The primary outcome will be the functionality of the affected upper extremity measured using the Fugl-Meyer Assessment. Secondary variables will include cognitive performance, emotional state, quality of life and activities of daily living. During 6 weeks, one of the intervention groups will receive a treatment based on MT and the other one on CTE, both combined with task-oriented training. No additional interventions will be provided to the control group. To assess the progress of patients who had a stroke in the subacute phase, all variables will be evaluated at different visits: initial (just before starting treatment and 4 weeks post-stroke), post-intervention (6 weeks after initial) and follow-up (6 months).Ethics and dissemination This protocol has been approved by the Institutional Review Board (CEIm-2.134/2.019) and registered at ClinicalTrials.gov (NCT04163666). The results will be disseminated through open-access peer-reviewed journals, conference presentation, broadcast media and a presentation to stakeholders. These study results will provide relevant and novel information on effective neurorehabilitation strategies and improve the quality of intervention programmes aimed at patients after a stroke.Trial registration number ClinicalTrials.gov (NCT04163666).
PB BMJ Publishing
SN 2044-6055
YR 2020
FD 2020-09
LK http://hdl.handle.net/10259/8635
UL http://hdl.handle.net/10259/8635
LA eng
NO The project leading to these results has received funding from “La Caixa” Foundation, under agreement LCF/PR/PR18/51130007
DS Repositorio Institucional de la Universidad de Burgos
RD 09-may-2024