RT info:eu-repo/semantics/article
T1 Silica-Immobilized NHC-Gold(I) Complexes: Versatile Catalysts for the Functionalization of Alkynes under Batch and Continuous Flow Conditions
A1 Sarmiento, Jeymy T.
A1 Suárez Pantiga, Samuel
A1 Olmos, Andrea
A1 Varea, Teresa
A1 Asensio, Gregorio
K1 Gold catalysis
K1 Immobilized catalyst
K1 Flow chemistry
K1 Alkyne
K1 NHC ligand
K1 Química orgánica
K1 Chemistry, Organic
AB Immobilized sterically demanding NHC-Au(I) complexes silica-[(IPrR)Au]Cl and silica-[(IAdPrR)Au]Cl are synthesized and characterized. These complexes are suitable catalysts in typical homogeneous Au(I)-catalyzed alkyne reactions such as hydration, hydroamination, hydroarylation, or cycloisomerization. The results obtained with the immobilized catalysts in reactions in batch are comparable to those obtained with their homogeneous counterparts with the advantage of easily recovered and recycled in successive reactions. Their catalytic activity decreases when reused in batch reactions, probably because of crushing that is associated with magnetic stirring. In contrast, these immobilized catalysts are very effective when used under continuous flow conditions in which the same cartridge can be used to catalyze different types of reaction successively for a long period without any noticeable loss of activity.
PB ACS Publications
SN 2155-5435
YR 2017
FD 2017-09
LK http://hdl.handle.net/10259/8647
UL http://hdl.handle.net/10259/8647
LA eng
NO Support for this work was provided by the Ministerio de Economı́a y Competitividad (MINECO) and European Community Founds (FEDER) (No. CTQ2014-52769-C3-2-R).
DS Repositorio Institucional de la Universidad de Burgos
RD 23-nov-2024