RT info:eu-repo/semantics/article T1 Cholesterol and Alzheimer’s Disease Risk: A Meta-Meta-Analysis A1 Sáiz Vázquez, Olalla A1 Puente Martínez, Alicia A1 Ubillos Landa, Silvia A1 Pacheco Bonrostro, Joaquín A1 Santabárbara, Javier K1 Alzheimer's disease K1 Etiology K1 Cholesterol K1 Risk factors K1 Meta-analysis K1 Medicina K1 Medicine K1 Salud K1 Health K1 Psicología K1 Psychology AB Alzheimer’s disease (AD) is the most common subtype of dementia. In the last ten years, the relationship between cholesterol and AD has been investigated. Evidence suggests that cholesterol is associated with AD and represents promising targets for intervention. However, the causality of these associations is unclear. Therefore, we sought to conduct a meta-meta-analysis to determine the effect of cholesterol on the development AD. Then, we assessed the effect of serum levels of low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C), total cholesterol (TC) and triglycerides (TG), on AD risk. PB MDPI YR 2020 FD 2020-06 LK http://hdl.handle.net/10259/8700 UL http://hdl.handle.net/10259/8700 LA eng NO This research was funded by a research grant from the Basque Country, Spain (awarded to A.P.), by the Junta of Castilla y León (Spain) to the Social Inclusion and Quality of Life (SIQoL) (No.665501), by FEDER funds and the Spanish Ministry of Economy and Competitiveness (Projects ECO2013-47129-C4-3-R and ECO2016-76567-C4-2-R), by the Regional Government of Castilla y León and FEDER funds (Projects BU329U14, BU071G19 and BU062U16), and by the Fondo de Investigación Sanitaria, Instituto de Salud Carlos III, Spanish Ministry of Economy and Competitiveness, Madrid, Spain (grants 94/1562, 97/1321E, 98/0103, 01/0255, 03/0815, 06/0617, G03/128, 19/01874). DS Repositorio Institucional de la Universidad de Burgos RD 22-dic-2024