RT info:eu-repo/semantics/article
T1 Neurological Disorders in Central Spain, Second Survey: Feasibility Pilot Observational Study
A1 Hernández Gallego, Jesús
A1 Llamas Velasco, Sara
A1 Bermejo Pareja, Félix
A1 Vega, Saturio
A1 Tapias Merino, Ester
A1 Rodríguez Sánchez, Emiliano
A1 Boycheva, Elina
A1 Serrano, José Ignacio
A1 Gil García, Juan Francisco
A1 Trincado, Rocío
A1 Vizcaino Sánchez-Rodrigo, José María
A1 Cacho, Jesús
A1 Contador, Israel
A1 García Ptacek, Sara
A1 Sierra Hidalgo, Fernando
A1 Cubo Delgado, Esther
A1 Carro, Eva
A1 Villarejo Galende, Alberto
A1 García García-Patino, Rosalía
A1 Benito-León, Julián
K1 Dementia
K1 Essential tremor
K1 Headache
K1 Longitudinal study
K1 Mild cognitive impairment
K1 NEDICES
K1 Observational study
K1 Parkinson’s disease
K1 Pilot study
K1 Population-based study
K1 Stroke
K1 Sistema nervioso-Enfermedades
K1 Nervous system-Diseases
K1 Neurología
K1 Neurology
K1 Medicina
K1 Medicine
AB Background:The Neurological Disorders in Central Spain, second survey (NEDICES-2) is a population-based, closed-cohort study that will include over 8000 subjects aged ≥55 years. It will also include a biobank.Objective:The objective of this study was to evaluate all major aspects of the NEDICES-2 (methods, database, screening instruments, and questionnaires, as well as interexpert rating of the neurological diagnoses) in each one of the planned areas (all of them in central Spain) and to test the possibility of obtaining biological samples from each participant.Methods:A selection of patients and participants of the planned NEDICES-2 underwent face-to-face interviews including a comprehensive questionnaire on demographics, current medications, medical conditions, and lifestyle habits. Biological samples (blood, saliva, urine, and hair) were also obtained. Furthermore, every participant was examined by a neurologist.Results:In this pilot study, 567 study participants were enrolled (196 from hospitals and 371 from primary care physician lists). Of these 567, 310 completed all study procedures (questionnaires and the neurological evaluation). The study was time-consuming for several primary care physicians. Hence, a few primary care physicians from some areas refused to participate, which led to a reconfiguration of study areas. In addition, the central biobank needed to be supplemented by the biobanks of local Spanish National Health System hospitals.Conclusions:Population-based epidemiological surveys, such as the NEDICES-2, require a pilot study to evaluate the feasibility of all aspects of a future field study (population selection, methods and instruments to be used, neurological diagnosis agreement, and data collection).
PB JMIR Publications
YR 2019
FD 2019-01
LK http://hdl.handle.net/10259/8785
UL http://hdl.handle.net/10259/8785
LA eng
DS Repositorio Institucional de la Universidad de Burgos
RD 09-may-2024