RT info:eu-repo/semantics/article
T1 Falls Predict Acute Hospitalization in Parkinson’s Disease
A1 Santos García, Diego
A1 Deus-Fonticoba, Teresa de
A1 Cores Bartolomé, Carlos
A1 Suárez Castro, Ester
A1 Hernández Vara, Jorge
A1 Jesús, Silvia
A1 Mir, Pablo
A1 Cosgaya, Marina
A1 José Martí, María
A1 Pastor, Pau
A1 Cabo López, Iria
A1 Seijo, Manuel
A1 Legarda, Inés
A1 Vives Pastor, Bárbara
A1 Caballol, Núria
A1 Ruíz Martínez, Javier
A1 Croitoru, Ioana
A1 Cubo Delgado, Esther
A1 Miranda, Javier
A1 Alonso Losada, María Gema
A1 Labandeira, Carmen
A1 López Ariztegui, Nuria
A1 Morales-Casado, Mabel
A1 González Aramburu, Isabel
A1 Infante, Jon
A1 Escalante Arroyo, Sonia
A1 Bernardo, Noemí
A1 Blázquez Estrada, Marta
A1 Menéndez González, Manuel
A1 García Caldentey, Juan
A1 Borrue, Carmen
A1 Vela Desojo, Lydia
A1 Catalán, María José
A1 Gómez Mayordomo, Víctor
A1 Kurtis, Mónica M.
A1 Prieto, Cristina
A1 Ordás Bandera, Carlos Manuel
A1 Nogueira, Víctor
A1 López Manzanares, Lydia
A1 Ávila Rivera, María A.
A1 Puente, Víctor
A1 García Moreno, José Manuel
A1 Solano Vila, Berta
A1 Álvarez Saúco, María
A1 Carrillo Padilla, Francisco
A1 Martínez Castrillo, Juan Carlos
A1 Sánchez Alonso, Pilar
A1 Gastón, Itziar
A1 Kulisevsky Bojarsky, Jaume
A1 Valero, Caridad
A1 Fabregues, Oriol de
A1 González Ardura, Jessica
A1 López Díaz, Luis M.
A1 Martínez Martín, Pablo
A1 COPPADIS Study Group
K1 Falls
K1 Hospitalization
K1 Non-motor symptoms
K1 Parkinson’s disease
K1 Predictors
K1 Sistema nervioso-Enfermedades
K1 Nervous system-Diseases
K1 Medicina
K1 Medicine
K1 Neurología
K1 Neurology
AB Background:There is a need for identifying risk factors for hospitalization in Parkinson’s disease (PD) and also interventions to reduce acute hospital admission.Objective:To analyze the frequency, causes, and predictors of acute hospitalization (AH) in PD patients from a Spanish cohort.Methods:PD patients recruited from 35 centers of Spain from the COPPADIS-2015 (COhort of Patients with PArkinson’s DIsease in Spain, 2015) cohort from January 2016 to November 2017, were included in the study. In order to identify predictors of AH, Kaplan-Meier estimates of factors considered as potential predictors were obtained and Cox regression performed on time to hospital encounter 1-year after the baseline visit.Results:Thirty-five out of 605 (5.8%) PD patients (62.5±8.9 years old; 59.8% males) presented an AH during the 1-year follow-up after the baseline visit. Traumatic falls represented the most frequent cause of admission, being 23.7% of all acute hospitalizations. To suffer from motor fluctuations (HR [hazard ratio] 2.461; 95% CI, 1.065–5.678; p = 0.035), a very severe non-motor symptoms burden (HR [hazard ratio] 2.828; 95% CI, 1.319–6.063; p = 0.008), falls (HR 3.966; 95% CI 1.757–8.470; p = 0.001), and dysphagia (HR 2.356; 95% CI 1.124–4.941; p = 0.023) was associated with AH after adjustment to age, gender, disease duration, levodopa equivalent daily dose, total number of non-antiparkinsonian drugs, and UPDRS-IIIOFF. Of the previous variables, only falls (HR 2.998; 95% CI 1.080–8.322; p = 0.035) was an independent predictor of AH.Conclusion:Falls is an independent predictor of AH in PD patients.
PB IOS Press
SN 1877-7171
YR 2023
FD 2023-01
LK http://hdl.handle.net/10259/8839
UL http://hdl.handle.net/10259/8839
LA eng
DS Repositorio Institucional de la Universidad de Burgos
RD 09-may-2024