RT info:eu-repo/semantics/article
T1 Direct synthesis of haloaromatics from nitroarenes via a sequential one-pot Mo-catalyzed reduction/Sandmeyer reaction
A1 Hernández Ruiz, Raquel
A1 Gómez Gil, Sara
A1 Pedrosa Sáez, María de los Remedios
A1 Suárez Pantiga, Samuel
A1 Sanz Díez, Roberto
K1 Química orgánica
K1 Chemistry, Organic
K1 Biología molecular
K1 Molecular biology
AB Herein, we report the direct synthesis of a wide variety of functionalized aromatic bromides, chlorides, iodides, and fluorides from nitroarenes in a sequential one-pot operation. This protocol is based on an air- and moisture-tolerant dioxomolybdenum-catalyzed reduction of nitroaromatics, employing pinacol as a reducing agent, which enables subsequent diazotization and halogenation steps. This methodology represents a step-economical, practical, and alternative procedure for synthesizing haloaromatics directly from nitroaromatics.
PB Royal Society of Chemistry
SN 1477-0520
YR 2023
FD 2023-09-08
LK http://hdl.handle.net/10259/9325
UL http://hdl.handle.net/10259/9325
LA eng
NO We gratefully acknowledge the Ministerio de Ciencia e Innovación MCIN/AEI/10.13039/501100011033 (PID2020-115789GB-C21) and the Junta de Castilla y León and FEDER (BU049P20) for financial support. R. H.-R. and S. G.-G. thank the Ministerio de Educación for FPU predoctoral contracts. S. S.-P. thanks the Ministerio de Ciencia e Innovación and the “NextGenerationEU”/PRTR EU for a Ramón y Cajal contract (RYC2021-031533-I).
DS Repositorio Institucional de la Universidad de Burgos
RD 25-dic-2024