RT info:eu-repo/semantics/article
T1 Synthesis of 4‐Furan‐ and 4‐Pyrrol‐3‐yl‐2H‐chromenes from Naturally‐occurring Compounds by Gold(I)‐Catalyed Domino Reactions
A1 Solas Luera, Marta
A1 Renedo Peña, Lorena
A1 Suárez Pantiga, Samuel
A1 Sanz Díez, Roberto
K1 Annulation
K1 Chromenes
K1 Furans
K1 Gold
K1 Hydroarylation
K1 Pyrroles
K1 Química orgánica
K1 Chemistry, Organic
AB A gold-catalyzed cascade double cyclization reaction has been designed to synthesize heterobiaryl compounds such as furanyl and pyrrolyl 2H-chromenes from bis(alkynyl)-1,2-diols and 1,2-amino alcohols. The starting materials are readily available from biomass platform molecules such as α-hydroxy acids and α-amino acids. The process involves an initial heterocyclodehydration step enabling the formation of the furan or pyrrole ring, followed by an alkyne hydroarylation to form the chromene core.
PB Wiley
SN 1615-4150
YR 2023
FD 2023-05-24
LK http://hdl.handle.net/10259/9336
UL http://hdl.handle.net/10259/9336
LA eng
NO We gratefully acknowledge Ministerio de Ciencia e Innovación MCIN/AEI/10.13039/501100011033 (PID2020–115789GB-C21), and Junta de Castilla y León and FEDER (BU049P20) for financial support. M.S. and L.R. thank Junta de Castilla y León (Consejería de Educación) and Fondo Social Europeo for predoctoral contracts. S.S.-P. thanks a Ramón y Cajal (RYC2021-031533-I) contract funded by MCIN/AEI/10.13039/501100011033 and European Union “NextGenerationEU”/PRTR.
DS Repositorio Institucional de la Universidad de Burgos
RD 23-nov-2024