RT info:eu-repo/semantics/article
T1 Exploring the bioactive potential of algae residue extract via subcritical water extraction: Insights into chemical composition and biological activity
A1 Trigueros Andrés, Ester
A1 Oliveira, Andreia P.
A1 Andrade, Paula B.
A1 Videira, Romeu A.
A1 Guedes de Pinho, Paula
A1 Sanz Díez, Mª Teresa
A1 Beltrán Calvo, Sagrario
K1 Macroalga residue
K1 Subcritical water
K1 Valorization
K1 Bioactivity
K1 Maillard reaction products
K1 Antioxidant activity
K1 Ingeniería química
K1 Chemical engineering
K1 Bioquímica
K1 Biochemistry
K1 Alimentos
K1 Food
K1 Biotecnología
K1 Biotechnology
AB Gelidium sesquipedale is valued in the Spanish agar industry, but its production generates substantial waste, often discarded despite its nutritional and bioactive content. Subcritical water extraction (SWE) at 175 °C and 50 bar for 130 min was performed on this waste after agar extraction, comparing it to conventional ethanol extraction. The SWE extract exhibited superior nutritional profile, including proteins (170.6 ± 1.0 mg/gfreeze-dried-extract), essential amino acids (18.1%), carbohydrates (148.1 ± 0.3 mg/gfreeze-dried-extract), total phenolic content (57 ± 7 mg-EqGA/gfreeze-dried-extract), and also containing Maillard reaction compounds, such as 5-hydroxymethylfurfural, furfural, 2-furanmethanol, 1-(2-furanyl)-ethanone, and 5-methyl-2-furfural, influencing color, aroma and flavor. This extract showed better antioxidant and anti-inflammatory properties than the conventional extract, and higher xanthine oxidase, tyrosinase, and acetylcholinesterase inhibition activities. Toxicological assessment on human cells indicated the safety of the SWE extract. Therefore, SWE technology offers a promising method to valorize G. sesquipedale residue, yielding a bioactive and nutrient-rich extract suitable for food and nutraceutical applications.
PB Elsevier
SN 0308-8146
YR 2024
FD 2024-11
LK http://hdl.handle.net/10259/9584
UL http://hdl.handle.net/10259/9584
LA eng
NO This work was supported by PT national funds (FCT/MCTES, Fundação para a Ciência e Tecnologia and Ministério da Ciência, Tecnologia e Ensino Superior) through the project UIDP/50006/2020. This work also had the financial support from the projects UIDP/04378/2020 and UIDB/04378/2020 of Research Unit on Applied Molecular Biosciences–UCIBIO and the project LA/P/0140/2020 from the Associate Laboratory Institute for Health and Bioeconomy–i4HB, and from the Spanish Ministerio de Ciencia e Innovación [grant number PDC2022–133443-I00] and Junta de Castilla y León and ERDF [grant number BU050P20].
DS Repositorio Institucional de la Universidad de Burgos
RD 23-nov-2024