RT info:eu-repo/semantics/article
T1 Liposomal Encapsulation of Oleuropein and an Olive Leaf Extract: Molecular Interactions, Antioxidant Effects and Applications in Model Food Systems
A1 González Ortega, Rodrigo
A1 Šturm, Luka
A1 Skrt, Mihaela
A1 Di Mattia, Carla Daniela
A1 Pittia, Paola
A1 Poklar Ulrih, Nataša
A1 Poklar
K1 Encapsulation
K1 Liposomes
K1 Oleuropein
K1 Olive leaf extract
K1 Phospholipid membranes
K1 Peroxidation
K1 Biotecnología alimentaria
K1 Food-Biotechnology
AB The influence of actively/passively encapsulated oleuropein on DPPC liposomes thermal and structural properties, and its antioxidant capacity against lipid peroxidation were investigated. Also, an oleuropein-rich olive leaf extract was encapsulated in soy phosphatidylcholine (PL-90 g) and incorporated in model and commercial drinks. Oleuropein induced a concentration-dependent broadening and splitting of the gel-to-liquid phase transition temperature. Fluorescence measurements revealed a fluidizing effect on liposomes below their gel-to-liquid phase transition temperature, and a higher lipid ordering above, especially to active encapsulation. Oleuropein also showed an antioxidant effect against lipid peroxidation in PL-90 g liposomes. PL-90 g Liposomes with olive leaf extract showed a mean diameter of 405 ± 4 nm and oleuropein encapsulation efficiency of 34% and delayed oleuropein degradation at pH 2.0 and 2.8 model drinks. In conclusion, greater effects were observed on the structure and fluidity of DPPC liposomes when oleuropein was actively encapsulated, while its incorporation into acidic foods in encapsulated form could enhance its stability.
PB Springer
SN 1557-1858
YR 2021
FD 2021-03
LK http://hdl.handle.net/10259/9972
UL http://hdl.handle.net/10259/9972
LA eng
NO This work was supported by the Italian Ministry of University and Research and has received funding from the European Union Horizon 2020 Research and Innovation Programme under the Marie Skłodowska-Curie grant agreement N° 713714, and by the Slovenian Research Agency under the P4-0121 Programme and the CRP V4-1621 Project.
DS Repositorio Institucional de la Universidad de Burgos
RD 30-ene-2025