TY  - JOUR 
AU  - Rodilla, Ananda M.
AU  - Korrodi Gregório, Luís
AU  - Hernando Santa Cruz, Elsa
AU  - Manuel Manresa, Pilar .
AU  - Quesada Pato, Roberto
AU  - Pérez Tomás, Ricardo
AU  - Soto Cerrato, Vanessa
PY  - 2017
UR  - http://hdl.handle.net/10259/4353
AB  - Current pharmacological treatments for lung cancer show very poor clinical outcomes, therefore, the development of novel anticancer agents with innovative mechanisms of action is urgently needed. Cancer cells have a reversed pH gradient compared to...
LA  - eng
PB  - Elsevier
KW  - Anionophores
KW  - Synthetictambjamine analogues
KW  - Lysosomal dysfunction
KW  - Autophagy blockade
KW  - Necrosis
KW  - Chemistry, Organic
KW  - Química orgánica
TI  - Synthetic tambjamine analogues induce mitochondrial swelling and lysosomal dysfunction leading to autophagy blockade and necrotic cell death in lung cancer
ER  -