TY  - JOUR 
AU  - Arias Betancur, Alain
AU  - Fontova Pale, Pere
AU  - Alonso Carrillo, Daniel
AU  - Carreira Barral, Israel
AU  - Duis, Janneke
AU  - García Valverde, María
AU  - Soto Cerrato, Vanessa
AU  - Quesada Pato, Roberto
AU  - Pérez Tomás, Ricardo
PY  - 2024
SN  - 0006-2952
UR  - http://hdl.handle.net/10259/9573
AB  - Due to the relevance of lactic acidosis in cancer, several therapeutic strategies have been developed targeting its production and/or regulation. In this matter, inhibition approaches of key proteins such as lactate dehydrogenase or monocarboxylate...
LA  - eng
PB  - Elsevier
KW  - Lactate
KW  - Anionophores
KW  - Click-tambjamines
KW  - Cancer metabolism
KW  - pH deregulation
KW  - Small molecules
KW  - Bioquímica
KW  - Biochemistry
KW  - Química orgánica
KW  - Chemistry, Organic
TI  - Deregulation of lactate permeability using a small-molecule transporter (Lactrans-1) disturbs intracellular pH and triggers cancer cell death
DO  - 10.1016/j.bcp.2024.116469
T2  - Biochemical Pharmacology
VL  - 229
M2  - 116469
ER  -