TY - JOUR AU - Herrero Gutiérrez, Ana AU - Sanllorente Méndez, Silvia AU - Reguera Alonso, Celia AU - Ortiz Fernández, Mª Cruz AU - Sarabia Peinador, Luis Antonio PY - 2016 UR - http://hdl.handle.net/10259/4357 AB - A new strategy to approach multiresponse optimization in conjunction to a D-optimal design for simultaneously optimizing a large number of experimental factors is proposed. The procedure is applied to the determination of biogenic amines (histamine,... LA - eng PB - Elsevier KW - Multiresponse optimization KW - D-optimal design KW - Biogenic amines KW - HPLC-FLD KW - Derivatization KW - Fish KW - Chemistry KW - Mathematics KW - Química KW - Matemáticas TI - A new multiresponse optimization approach in combination with a D-Optimal experimental design for the determination of biogenic amines in fish by HPLC-FLD ER -