TY - JOUR AU - Pérez Arnáiz, Cristina AU - Busto Vázquez, Natalia AU - Santolaya, Javier AU - Leal Villalba, José María AU - Barone, Giampaolo AU - García Ruiz, Begoña PY - 2018 SN - 0304-4165 UR - http://hdl.handle.net/10259/4746 AB - Background: Stabilization of G-quadruplex helices by small ligands has attracted growing attention because they inhibit the activity of the enzyme telomerase, which is overexpressed in> 80% cancer cells. TMPyP4, one of the most studied G-quadruplex... LA - eng PB - Elsevier KW - Tel22 conformations KW - TMPyP4 KW - Fast reactions KW - Molecular dynamics KW - Chemistry, Physical and theoretical KW - Química física TI - Kinetic evidence for interaction of TMPyP4 with two different G-quadruplex conformations of human telomeric DNA DO - 10.1016/j.bbagen.2017.10.020 ER -