TY - JOUR AU - Benito, José M. . AU - Ortiz Fernández, Mª Cruz AU - León, Agathe . AU - Sarabia Peinador, Luis Antonio AU - Ligos, José M. . AU - Montoya, María . AU - García, Marcial . AU - Ruiz Mateos, Ezequiel . AU - Palacios, Rosario . AU - Cabello, Alfonso . AU - Restrepo, Clara . AU - Rodríguez, Carmen . AU - Romero, Jorge del . AU - Leal, Manuel . AU - Muñoz Fernández, María A. . AU - Alcamí, José . AU - García, Felipe . AU - Górgolas, Miguel . AU - Rallón, Norma . PY - 2018 SN - 1741-7015 UR - http://hdl.handle.net/10259/4747 AB - Despite long-lasting HIV replication control, a significant proportion of elite controller (EC) patients may experience CD4 T-cell loss. Discovering perturbations in immunological parameters could help our understanding of the mechanisms that may be... LA - eng PB - BioMed Central KW - Elite controllers KW - CD4 T-cell loss KW - Class modeling KW - T-cell homeostatic parameters KW - CD8 exhaustion KW - Chemistry KW - Mathematics KW - Química KW - Matemáticas TI - Class-modeling analysis reveals T-cell homeostasis disturbances involved in loss of immune control in elite controllers DO - 10.1186/s12916-018-1026-6 ER -