TY  - JOUR 
AU  - Ayllón Barasoain, Juan
AU  - Hale, Benjamin G.
AU  - García Sastre, Adolfo
PY  - 2012
SN  - 0022-538X
UR  - http://hdl.handle.net/10259/9525
AB  - We generated influenza A viruses expressing mutant NS1 proteins unable to activate phosphoinositide 3-kinase (PI3K) in two
mouse-lethal strains. The recombinant A/Puerto Rico/8/34 (rPR8) mutant virus strain was attenuated and caused reduced...
LA  - eng
PB  - American Society for Microbiology
KW  - Medicina
KW  - Medicine
KW  - Salud
KW  - Health
KW  - Microbiología
KW  - Microbiology
KW  - Enfermedades infecciosas
KW  - Communicable diseases
TI  - Strain-Specific Contribution of NS1-Activated Phosphoinositide 3-Kinase Signaling to Influenza A Virus Replication and Virulence
DO  - 10.1128/jvi.06722-11
T2  - Journal of Virology
VL  - 86
M2  - 5366
ER  -