TY - JOUR AU - Ayllón Barasoain, Juan AU - Russell, Rupert J. AU - García Sastre, Adolfo AU - Hale, Benjamin G. PY - 2012 SN - 0022-538X UR - http://hdl.handle.net/10259/9528 AB - Conserved tryptophan-187 facilitates homodimerization of the influenza A virus NS1 protein effector domain. We generated a mutant influenza virus strain expressing NS1-W187R to destabilize this self-interaction. NS1-W187R protein exhibited lower... LA - eng PB - American Society for Microbiology KW - Medicina KW - Medicine KW - Salud KW - Health KW - Microbiología KW - Microbiology KW - Enfermedades infecciosas KW - Communicable diseases TI - Contribution of NS1 Effector Domain Dimerization to Influenza A Virus Replication and Virulence DO - 10.1128/jvi.02237-12 ER -